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NCT02258685 · ClinicalTrials.gov registry record
Factors Mediating Gut Microbiota Dysbiosis and Metabolic Disease in HIV Patients.
A clinical trial, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- 93
- Enrollment target
NCT02258685: Completed study, sponsored by University of Colorado, Denver.
NCT02258685 is a clinical trial that has completed, run by University of Colorado, Denver. The registered enrollment target is 93 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02258685 has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- 93 participants
- Enrollment target
Study Summary
This study plans to learn more about immune responses in intestinal (gut) tissue in people with human immunodeficiency virus (HIV) infection. This study will determine whether change in the composition of gut bacteria in HIV infected individuals is related to a high prevalence of chronic gut inflammation and metabolic disease. The investigators will also investigate immune-modulatory properties of specific bacteria that correlate with disease both by characterizing which functional genes are selected for in their genomes and by stimulating immune cells isolated from blood and gut tissue with bacterial isolates. This work will establish whether gain/loss of bacterial drivers/suppressors of information in the gut contributes to metabolic disease in HIV-infected individuals.
Primary Outcome
Compare the gut microbiota composition of HIV-positive subjects with and without lipodystrophy and long-term ART, and HIV-negative controls with diet and metabolic and immune activation markers in blood.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 93 participants |
| Start Date | 2014-11 |
| Est. Completion | 2019-07 |
What the finished NCT02258685 record still lists
NCT02258685 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 93 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02258685 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02258685 about?
NCT02258685 is a clinical study titled "Factors Mediating Gut Microbiota Dysbiosis and Metabolic Disease in HIV Patients.". This study plans to learn more about immune responses in intestinal (gut) tissue in people with human immunodeficiency virus (HIV) infection. This study will determine whether change in the composition of gut bacteria in HIV infected individuals is related to a high prevalence of chronic gut inflamm...
What is the current status of trial NCT02258685?
This trial is currently completed. The enrollment target is 93 participants. The study started on 2014-11. Estimated completion is 2019-07.
Who is sponsoring clinical trial NCT02258685?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
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