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NCT02254681 · ClinicalTrials.gov registry record · Phase 2

Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHC

A Phase 2 study, sponsored by Allina Health System.

Terminated
Registry status
Phase 2
Development phase
6
Enrollment target

NCT02254681: Clinical Trial Phase 2 study, sponsored by Allina Health System.

NCT02254681 is a Phase 2 study that was terminated before completion, run by Allina Health System. The registered enrollment target is 6 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02254681, a Phase 2 study, was terminated before completion, sponsored by Allina Health System.

TERMINATED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

The overall goal of this study is to determine the safety and efficacy of combination treatment of low-dose fractionated radiation therapy with gemcitabine-cisplatin chemotherapy for locally advanced mass forming intra-hepatic cholangiocarcinoma.

Primary Outcome

Per Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.1) for target lesions and assessed by CT/MRI: Complete Response (CR), Disappearance of all target lesions; Partial Response (PR), \>=30% decrease in the sum of the longest diameter of target lesions; Progressive Disease (PD), At least a 20% increase in the sum of the diameters of target lesions, taking as reference the smallest sum on study (this includes the baseline sum if that is the smallest on study).

Interventions

  • DRUG Cisplatin
  • DRUG Gemcitabine
  • RADIATION low dose radiotherapy

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2014-09
Est. Completion 2016-09
Phase Phase 2
Allina Health System

32 total trials

Why NCT02254681 stopped before completion

NCT02254681 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 3 interventions - of which Cisplatin is the first listed.

NCT02254681 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02254681 about?

NCT02254681 is a clinical study titled "Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHC". The overall goal of this study is to determine the safety and efficacy of combination treatment of low-dose fractionated radiation therapy with gemcitabine-cisplatin chemotherapy for locally advanced mass forming intra-hepatic cholangiocarcinoma.

What is the current status of trial NCT02254681?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2014-09. Estimated completion is 2016-09.

What interventions are being tested in trial NCT02254681?

The interventions under investigation include: Cisplatin (DRUG), Gemcitabine (DRUG), low dose radiotherapy (RADIATION).

Who is sponsoring clinical trial NCT02254681?

This trial is sponsored by Allina Health System, which has 32 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02254681's enrollment target sits among peer trials

6 1996th of 2000 higher than 1 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02254681, the US trial registry maintained by the National Library of Medicine. NCT02254681 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.