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NCT02249325 · ClinicalTrials.gov registry record · NA

Quasi Experiment of Prenatal Probiotics Against Group B Streptococcus Colonization

A NA study, sponsored by Marquette University.

Completed
Registry status
NA
Development phase
20
Enrollment target

NCT02249325: Completed NA study, sponsored by Marquette University.

NCT02249325 is a NA study that has completed, run by Marquette University. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02249325, a NA study, has completed, sponsored by Marquette University.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

This pilot quasi experiment was designed to determine the feasibility of a randomized controlled trial of the oral probiotic combination of Florajen3 (\>7.5 x109 L. acidophilus, \>6.0 x109. B. lactis, and \>1.5 x109 B. longum) taken orally once daily beginning at 28 weeks gestation, against placebo, to reduce the colonization of group B Streptococcus at 36 weeks.

Primary Outcome

Routine prenatal GBS cultures were collected on all study participants at 35-37 weeks gestation as per the 2010 CDC GBS prevention guidelines. Only this result was use to determined the need for intrapartum antibiotic prophylaxis. All study participants received separate vaginal and rectal GBS culture swabs that were analyzed quantitatively for GBS/swab in Colony Forming Units (CFUs). These results were blind to the prenatal care providers.

Interventions

  • DIETARY_SUPPLEMENT Probiotic dietary supplement

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2011-01
Est. Completion 2013-06
Phase NA
Marquette University

27 total trials

What the finished NCT02249325 record still lists

NCT02249325 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Probiotic dietary supplement is the first listed.

NCT02249325 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02249325 about?

NCT02249325 is a clinical study titled "Quasi Experiment of Prenatal Probiotics Against Group B Streptococcus Colonization". This pilot quasi experiment was designed to determine the feasibility of a randomized controlled trial of the oral probiotic combination of Florajen3 (\>7.5 x109 L. acidophilus, \>6.0 x109. B. lactis, and \>1.5 x109 B. longum) taken orally once daily beginning at 28 weeks gestation, against placebo,...

What is the current status of trial NCT02249325?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2011-01. Estimated completion is 2013-06.

What interventions are being tested in trial NCT02249325?

The interventions under investigation include: Probiotic dietary supplement (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT02249325?

This trial is sponsored by Marquette University, which has 27 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02249325's enrollment target sits among peer trials

20 1768th of 2000 higher than 140 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02249325, the US trial registry maintained by the National Library of Medicine. NCT02249325 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.