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NCT02248818 · ClinicalTrials.gov registry record · Phase 1
AZD8108 SAD/MAD in Healthy Volunteers
A Phase 1 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 1
- Development phase
- 258
- Enrollment target
NCT02248818: Completed Phase 1 study, sponsored by AstraZeneca.
NCT02248818 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 258 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (330% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02248818, a Phase 1 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 258 participants
- Enrollment target
Study Summary
This is a randomized, double-blind, placebo-controlled study of single and multiple ascending dosage levels of AZD8108 in healthy volunteers. The study includes an up to 28-day screening period, an in-house period during which AZD8108 or placebo will be administered orally as a solution, and a 4- to 10-day follow-up period after discharge.
Primary Outcome
Safety Laboratory - Thyroid Stimulating Hormone participants with laboratory value above the upper limit of normal
Interventions
- DRUG Placebo
- DRUG AZD8108
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 258 participants |
| Start Date | 2014-11 |
| Est. Completion | 2015-09 |
| Phase | Phase 1 |
What the finished NCT02248818 record still lists
NCT02248818 is an interventional study that assigns participants to a tested intervention. The registered 258 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (330% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02248818 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02248818 about?
NCT02248818 is a clinical study titled "AZD8108 SAD/MAD in Healthy Volunteers". This is a randomized, double-blind, placebo-controlled study of single and multiple ascending dosage levels of AZD8108 in healthy volunteers. The study includes an up to 28-day screening period, an in-house period during which AZD8108 or placebo will be administered orally as a solution, and a 4- to...
What is the current status of trial NCT02248818?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 258 participants. The study started on 2014-11. Estimated completion is 2015-09.
What interventions are being tested in trial NCT02248818?
The interventions under investigation include: Placebo (DRUG), AZD8108 (DRUG).
Who is sponsoring clinical trial NCT02248818?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02248818's enrollment target sits among peer trials
258 167th of 2000 higher than 1,833 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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