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NCT02240355 · ClinicalTrials.gov registry record · Phase 1

A Study of RO6885247 in Adult and Pediatric Patients With Spinal Muscular Atrophy (MOONFISH)

A Phase 1 study, sponsored by Hoffmann-La Roche.

Terminated
Registry status
Phase 1
Development phase
9
Enrollment target

NCT02240355: Clinical Trial Phase 1 study, sponsored by Hoffmann-La Roche.

NCT02240355 is a Phase 1 study that was terminated before completion, run by Hoffmann-La Roche. The registered enrollment target is 9 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02240355, a Phase 1 study, was terminated before completion, sponsored by Hoffmann-La Roche.

TERMINATED
Registry status
Phase 1
Development phase
9 participants
Enrollment target

Study Summary

This multicenter, randomized, double-blind, 12-week, placebo-controlled multiple dose study will investigate the safety and tolerability of RO6885247 in adult and pediatric patients with spinal muscular atrophy (SMA).

Interventions

  • DRUG placebo
  • DRUG RO6885247

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2014-11
Est. Completion 2015-07
Phase Phase 1
Hoffmann-La Roche

909 total trials

Why NCT02240355 stopped before completion

NCT02240355 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT02240355 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02240355 about?

NCT02240355 is a clinical study titled "A Study of RO6885247 in Adult and Pediatric Patients With Spinal Muscular Atrophy (MOONFISH)". This multicenter, randomized, double-blind, 12-week, placebo-controlled multiple dose study will investigate the safety and tolerability of RO6885247 in adult and pediatric patients with spinal muscular atrophy (SMA).

What is the current status of trial NCT02240355?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2014-11. Estimated completion is 2015-07.

What interventions are being tested in trial NCT02240355?

The interventions under investigation include: placebo (DRUG), RO6885247 (DRUG).

Who is sponsoring clinical trial NCT02240355?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02240355's enrollment target sits among peer trials

9 1955th of 2000 higher than 42 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02240355, the US trial registry maintained by the National Library of Medicine. NCT02240355 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.