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NCT02229032 · ClinicalTrials.gov registry record
Genetic Analysis Between Charlotte's Web Responders Versus Non- Responders in a Dravet Population
A clinical trial, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- 19
- Enrollment target
NCT02229032: Completed study, sponsored by University of Colorado, Denver.
NCT02229032 is a clinical trial that has completed, run by University of Colorado, Denver. The registered enrollment target is 19 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02229032 has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- 19 participants
- Enrollment target
Study Summary
There is tremendous curiosity about medical marijuana and the treatment of epilepsy. In a specific genetic epilepsy known as Dravet Syndrome, a mutation occurs affecting the SCN1A gene. A specific strain of marijuana known as Charlotte's Web, available in Colorado, may have activity in this catastrophic epilepsy syndrome. Anecdotal reports suggest both success and lack of response with this therapy. Genetic analysis of the differences between Dravet responders and non-responders may prove useful for identifying patients likely to be helped by this therapy, as well as shed light on the putative mechanisms by which marijuana may exert any antiepileptic effect.
Primary Outcome
Patients completing three months of therapy with a seizure reduction of \>50% will be designated a "Responder" and patients who discontinue therapy for any reason prior to 3 months or have a \<=50% seizure reduction will be designated "Non-Responder". Between-groups genetic analysis will be performed
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2014-08 |
| Est. Completion | 2017-07 |
What the finished NCT02229032 record still lists
NCT02229032 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 19 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02229032 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02229032 about?
NCT02229032 is a clinical study titled "Genetic Analysis Between Charlotte's Web Responders Versus Non- Responders in a Dravet Population". There is tremendous curiosity about medical marijuana and the treatment of epilepsy. In a specific genetic epilepsy known as Dravet Syndrome, a mutation occurs affecting the SCN1A gene. A specific strain of marijuana known as Charlotte's Web, available in Colorado, may have activity in this catastro...
What is the current status of trial NCT02229032?
This trial is currently completed. The enrollment target is 19 participants. The study started on 2014-08. Estimated completion is 2017-07.
Who is sponsoring clinical trial NCT02229032?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
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