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NCT02227173 · ClinicalTrials.gov registry record · Phase 1
A Phase 1 Drug-drug Interaction Study in Healthy Volunteers
A Phase 1 study, sponsored by Bristol-Myers Squibb.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT02227173: Completed Phase 1 study, sponsored by Bristol-Myers Squibb.
NCT02227173 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02227173, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
This is an open-label, single-sequence, drug-drug interaction study in healthy male and female subjects. There is no formal research hypothesis to be statistically tested. It is expected that coadministration of BMS-986020 with montelukast, flurbiprofen, and digoxin may increase the exposure of montelukast, flurbiprofen, and digoxin.
Primary Outcome
Pharmacokinetic endpoints for montelukast, flurbiprofen, and digoxin with and without BMS-986020
Interventions
- DRUG Montelukast
- DRUG Digoxin
- DRUG BMS-986020
- DRUG Flurbiprofen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2014-09 |
| Est. Completion | 2014-11 |
| Phase | Phase 1 |
What the finished NCT02227173 record still lists
NCT02227173 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 4 interventions - of which Montelukast is the first listed.
NCT02227173 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02227173 about?
NCT02227173 is a clinical study titled "A Phase 1 Drug-drug Interaction Study in Healthy Volunteers". This is an open-label, single-sequence, drug-drug interaction study in healthy male and female subjects. There is no formal research hypothesis to be statistically tested. It is expected that coadministration of BMS-986020 with montelukast, flurbiprofen, and digoxin may increase the exposure of mont...
What is the current status of trial NCT02227173?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2014-09. Estimated completion is 2014-11.
What interventions are being tested in trial NCT02227173?
The interventions under investigation include: Montelukast (DRUG), Digoxin (DRUG), BMS-986020 (DRUG), Flurbiprofen (DRUG).
Who is sponsoring clinical trial NCT02227173?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02227173's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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