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NCT02214628 · ClinicalTrials.gov registry record · Phase 2

Phase 2A Open Label Safety Study of Fovista® (Anti-PDGF BB) Regimen Administered in Combination With Anti-VEGF Therapy to Study Sub-Retinal Fibrosis in Neovascular AMD

A Phase 2 study, sponsored by Ophthotech Corporation.

Terminated
Registry status
Phase 2
Development phase
101
Enrollment target

NCT02214628: Clinical Trial Phase 2 study, sponsored by Ophthotech Corporation.

NCT02214628 is a Phase 2 study that was terminated before completion, run by Ophthotech Corporation. The registered enrollment target is 101 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (24% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT02214628, a Phase 2 study, was terminated before completion, sponsored by Ophthotech Corporation.

TERMINATED
Registry status
Phase 2
Development phase
101 participants
Enrollment target

Study Summary

The objective is to evaluate the safety of intravitreal Fovista® (anti-PDGF BB) administered in combination with anti-VEGF therapy.

Primary Outcome

Number of subjects on either arm with non-serious adverse events (reported by \>5% of subjects)

Interventions

  • DRUG Fovista® (anti-PDGF BB) plus anti-VEGF

Trial Details

FieldValue
Enrollment Target 101 participants
Start Date 2014-07
Est. Completion 2016-12
Phase Phase 2
Ophthotech Corporation

11 total trials

Why NCT02214628 stopped before completion

NCT02214628 is an interventional study that assigns participants to a tested intervention. The registered 101 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (24% lower).

The record links to 0 conditions, and to 1 intervention - of which Fovista® (anti-PDGF BB) plus anti-VEGF is the first listed.

NCT02214628 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02214628 about?

NCT02214628 is a clinical study titled "Phase 2A Open Label Safety Study of Fovista® (Anti-PDGF BB) Regimen Administered in Combination With Anti-VEGF Therapy to Study Sub-Retinal Fibrosis in Neovascular AMD". The objective is to evaluate the safety of intravitreal Fovista® (anti-PDGF BB) administered in combination with anti-VEGF therapy.

What is the current status of trial NCT02214628?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 101 participants. The study started on 2014-07. Estimated completion is 2016-12.

What interventions are being tested in trial NCT02214628?

The interventions under investigation include: Fovista® (anti-PDGF BB) plus anti-VEGF (DRUG).

Who is sponsoring clinical trial NCT02214628?

This trial is sponsored by Ophthotech Corporation, which has 11 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02214628's enrollment target sits among peer trials

101 672nd of 2000 higher than 1,329 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02214628, the US trial registry maintained by the National Library of Medicine. NCT02214628 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.