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NCT02207907 · ClinicalTrials.gov registry record · Phase 2
To Evaluate the Efficacy and Tolerability of Sodium Bicarbonate Toothpaste
A Phase 2 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 2
- Development phase
- 247
- Enrollment target
NCT02207907: Completed Phase 2 study, sponsored by GlaxoSmithKline.
NCT02207907 is a Phase 2 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 247 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02207907, a Phase 2 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 247 participants
- Enrollment target
Study Summary
The primary objectives of this study will be to compare the Gingival Bleeding and Gingival Inflammation following twice daily use of a sodium bicarbonate experimental dentifrice compared to a 0% sodium bicarbonate toothpaste after 24 weeks of use. The study will be conducted at Silverstone Research Group. Participants will be recruited from their database and by use of an external recruitment agency.
Primary Outcome
Number of gingival bleeding sites were measured as bleeding index via a single examiner using a color coded periodontal probe. The probe was engaged approximately 1 millimetre (mm) into the gingival crevice. A moderate pressure was used whilst sweeping from interproximal to interproximal along the sulcular epithelium. The BI scoring system used to measure bleeding sites is as follows: 0= No bleeding after 30 seconds; 1= Bleeding upon probing after 30 seconds; 2= Immediate bleeding observed. A bl
Interventions
- DRUG Sodium fluoride
- DRUG Sodium bicarbonate plus sodium fluoride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 247 participants |
| Start Date | 2014-08 |
| Est. Completion | 2015-03 |
| Phase | Phase 2 |
What the finished NCT02207907 record still lists
NCT02207907 is an interventional study that assigns participants to a tested intervention. The registered 247 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% higher).
The record links to 0 conditions, and to 2 interventions - of which Sodium fluoride is the first listed.
NCT02207907 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02207907 about?
NCT02207907 is a clinical study titled "To Evaluate the Efficacy and Tolerability of Sodium Bicarbonate Toothpaste". The primary objectives of this study will be to compare the Gingival Bleeding and Gingival Inflammation following twice daily use of a sodium bicarbonate experimental dentifrice compared to a 0% sodium bicarbonate toothpaste after 24 weeks of use. The study will be conducted at Silverstone Research ...
What is the current status of trial NCT02207907?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 247 participants. The study started on 2014-08. Estimated completion is 2015-03.
What interventions are being tested in trial NCT02207907?
The interventions under investigation include: Sodium fluoride (DRUG), Sodium bicarbonate plus sodium fluoride (DRUG).
Who is sponsoring clinical trial NCT02207907?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02207907's enrollment target sits among peer trials
247 234th of 2000 higher than 1,767 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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