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NCT02206087 · ClinicalTrials.gov registry record · Phase 1

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PER977 Following Heparin

A Phase 1 study, sponsored by Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
60
Enrollment target

NCT02206087: Completed Phase 1 study, sponsored by Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals.

NCT02206087 is a Phase 1 study that has completed, run by Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals. The registered enrollment target is 60 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02206087, a Phase 1 study, has completed, sponsored by Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
60 participants
Enrollment target

Study Summary

Normal subjects will receive unfractionated heparin followed by a single dose of PER977 with dose escalation by cohort. Ten subjects enrolled in Cohort 4 will receive a single dose of PER977 followed by a one-week washout and then will receive unfractionated heparin followed by a single dose of PER977. The study will provide some insight into the doses that may be required to reverse anticoagulation induced by heparin.

Interventions

  • DRUG Placebo
  • DRUG PER977
  • DRUG Heparin Sodium

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2014-06
Est. Completion 2016-03
Phase Phase 1

What the Registry Record Tells You About NCT02206087

The ClinicalTrials.gov registry entry for NCT02206087 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02206087 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02206087 about?

NCT02206087 is a clinical study titled "Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PER977 Following Heparin". Normal subjects will receive unfractionated heparin followed by a single dose of PER977 with dose escalation by cohort. Ten subjects enrolled in Cohort 4 will receive a single dose of PER977 followed by a one-week washout and then will receive unfractionated heparin followed by a single dose of PER9...

What is the current status of trial NCT02206087?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2014-06. Estimated completion is 2016-03.

What interventions are being tested in trial NCT02206087?

The interventions under investigation include: Placebo (DRUG), PER977 (DRUG), Heparin Sodium (DRUG).

Who is sponsoring clinical trial NCT02206087?

This trial is sponsored by Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, which has 9 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.