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NCT02203162 · ClinicalTrials.gov registry record · Phase 4

Effect of Electronic Cigarette Use on Cough Reflex Sensitivity

A Phase 4 study, sponsored by Montefiore Medical Center.

Completed
Registry status
Phase 4
Development phase
30
Enrollment target

NCT02203162: Completed Phase 4 study, sponsored by Montefiore Medical Center.

NCT02203162 is a Phase 4 study that has completed, run by Montefiore Medical Center. The registered enrollment target is 30 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02203162, a Phase 4 study, has completed, sponsored by Montefiore Medical Center.

COMPLETED
Registry status
Phase 4
Development phase
30 participants
Enrollment target

Study Summary

Although electronic cigarettes (e-cigs) are now widely used, very little information exists regarding the effect of electronic cigarette use (vaping) on the respiratory system. The aim of this study is to evaluate the acute effect of one e-cig vaping session (30 puffs 30 seconds apart) on cough reflex sensitivity in healthy adult nonsmokers.

Primary Outcome

Measurement of cough reflex sensitivity to capsaicin (C5) performed 15 minutes and 24 hours after electronic cigarette use session. Changes in cough reflex sensitivity 15 minutes after e-cig use compared to baseline will be assessed. In addition, cough reflex sensitivity 24 hours after e-cig exposure will also be measured, so that duration of any changes noted after 15 minutes can be assessed. Increase in C5 means decrease in cough reflex sensitivity. Capsaicin cough challenge involves subjects

Interventions

  • DEVICE electronic cigarette exposure

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2014-07
Est. Completion 2014-12
Phase Phase 4
Montefiore Medical Center

345 total trials

What the finished NCT02203162 record still lists

NCT02203162 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 1 intervention - of which electronic cigarette exposure is the first listed.

NCT02203162 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02203162 about?

NCT02203162 is a clinical study titled "Effect of Electronic Cigarette Use on Cough Reflex Sensitivity". Although electronic cigarettes (e-cigs) are now widely used, very little information exists regarding the effect of electronic cigarette use (vaping) on the respiratory system. The aim of this study is to evaluate the acute effect of one e-cig vaping session (30 puffs 30 seconds apart) on cough refl...

What is the current status of trial NCT02203162?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2014-07. Estimated completion is 2014-12.

What interventions are being tested in trial NCT02203162?

The interventions under investigation include: electronic cigarette exposure (DEVICE).

Who is sponsoring clinical trial NCT02203162?

This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02203162's enrollment target sits among peer trials

30 1552nd of 2000 higher than 367 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02203162, the US trial registry maintained by the National Library of Medicine. NCT02203162 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.