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NCT02199964 · ClinicalTrials.gov registry record · NA
The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular Surface
A NA study, sponsored by Baylor College of Medicine.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT02199964: Clinical Trial NA study, sponsored by Baylor College of Medicine.
NCT02199964 is a NA study that was terminated before completion, run by Baylor College of Medicine. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02199964, a NA study, was terminated before completion, sponsored by Baylor College of Medicine.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
This study will test that hypothesis that topical administration of the FDA approved immunomodulatory agent cyclosporin A emulsion will minimize irritation and ocular surface disease that results from a short term low humidity environmental stress
Primary Outcome
The mean difference in corneal staining using the adjusted CCLR global staining score before and after the environmental challenge at visits baseline and Visit 3/Day 42 when patients were subjected to a 90-minute low humidity stress. Corneal fluorescein staining was graded 0-100 in 5 zones on the cornea. The scores ranged from 0 (minimum) to 500 (maximum). A higher score indicates there was greater cornea disease induced by the low humidity stress on Day 42
Interventions
- DRUG Cyclosporin 0.05% emulsion
- DRUG Endura, Refresh artificial tears
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2014-03 |
| Est. Completion | 2015-12 |
| Phase | NA |
Why NCT02199964 stopped before completion
NCT02199964 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Cyclosporin 0.05% emulsion is the first listed.
NCT02199964 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02199964 about?
NCT02199964 is a clinical study titled "The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular Surface". This study will test that hypothesis that topical administration of the FDA approved immunomodulatory agent cyclosporin A emulsion will minimize irritation and ocular surface disease that results from a short term low humidity environmental stress
What is the current status of trial NCT02199964?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2014-03. Estimated completion is 2015-12.
What interventions are being tested in trial NCT02199964?
The interventions under investigation include: Cyclosporin 0.05% emulsion (DRUG), Endura, Refresh artificial tears (DRUG).
Who is sponsoring clinical trial NCT02199964?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02199964's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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