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NCT02196259 · ClinicalTrials.gov registry record · NA
Anesthesia and Functional Connectivity: An Analysis of fMRI Changes
A NA study, sponsored by University of Michigan.
- Terminated
- Registry status
- NA
- Development phase
- 16
- Enrollment target
NCT02196259 is a NA study that was terminated before completion, run by University of Michigan. The registered enrollment target is 16 participants.
The verdict
NCT02196259, a NA study, was terminated before completion, sponsored by University of Michigan.
- TERMINATED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
Study Summary
Functional connectivity is defined as a correlation in neural activity between distinct regions of the brain. Several recent studies have demonstrated areas of low-frequency functional connectivity inherent to brain tissue at rest. These oscillations can be measured using functional magnetic resonance imaging (fMRI) and appear to be synchronized between related areas of the brain. To date, no investigators have examined the effects of low-dose anesthesia on functional connectivity. This study will image the human brain under conditions of rest, and low-dose anesthetic induced sedation. Quality of the acquired signals will be evaluated and functional networks in the brain will be examined. Of interest is whether administration of a low-dose anesthetic disrupts functional connectivity in the brain, and whether a disruption of functional connectivity is responsible for the reported analgesic and antidepressant effects of a anesthetic. Participation in the study includes four visits: an in-person interview, an initial fMRI scan, the anesthesia infusion, and a second fMRI scan. There is an optional follow-up fMRI scan one week post infusion.
Interventions
- DRUG Anesthetics, Dissociative
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2008-02 |
| Est. Completion | 2015-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02196259
The ClinicalTrials.gov registry entry for NCT02196259 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Anesthetics, Dissociative is the first listed.
NCT02196259 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02196259 about?
NCT02196259 is a clinical study titled "Anesthesia and Functional Connectivity: An Analysis of fMRI Changes". Functional connectivity is defined as a correlation in neural activity between distinct regions of the brain. Several recent studies have demonstrated areas of low-frequency functional connectivity inherent to brain tissue at rest. These oscillations can be measured using functional magnetic resonan...
What is the current status of trial NCT02196259?
This trial is currently terminated. It is a NA study. The enrollment target is 16 participants. The study started on 2008-02. Estimated completion is 2015-05.
What interventions are being tested in trial NCT02196259?
The interventions under investigation include: Anesthetics, Dissociative (DRUG).
Who is sponsoring clinical trial NCT02196259?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
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