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NCT02194049 · ClinicalTrials.gov registry record · Phase 1

Cisplatin, Etoposide and PI3K Inhibitor BKM120 in Treating Patients With Advanced Solid Tumors or Small Cell Lung Cancer

A Phase 1 study, sponsored by University of California, Davis.

Completed
Registry status
Phase 1
Development phase
3
Enrollment target

NCT02194049 is a Phase 1 study that has completed, run by University of California, Davis. The registered enrollment target is 3 participants.

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The verdict

NCT02194049, a Phase 1 study, has completed, sponsored by University of California, Davis.

COMPLETED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and the best dose of PI3K inhibitor BKM120 when given together with cisplatin and etoposide in treating patients with advanced solid tumors or small cell lung cancer. Drugs used in chemotherapy, such as cisplatin and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing , or by stopping them from spreading. PI3K inhibitor BKM120 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving PI3K inhibitor BKM120 with cisplatin and etoposide may kill more tumor cells.

Interventions

  • DRUG cisplatin
  • DRUG etoposide
  • DRUG BKM120

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2014-07
Est. Completion 2016-06
Phase Phase 1

Sponsor

University of California, Davis

657 total trials

What the Registry Record Tells You About NCT02194049

The ClinicalTrials.gov registry entry for NCT02194049 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which cisplatin is the first listed.

NCT02194049 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02194049 about?

NCT02194049 is a clinical study titled "Cisplatin, Etoposide and PI3K Inhibitor BKM120 in Treating Patients With Advanced Solid Tumors or Small Cell Lung Cancer". This phase I trial studies the side effects and the best dose of PI3K inhibitor BKM120 when given together with cisplatin and etoposide in treating patients with advanced solid tumors or small cell lung cancer. Drugs used in chemotherapy, such as cisplatin and etoposide, work in different ways to st...

What is the current status of trial NCT02194049?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2014-07. Estimated completion is 2016-06.

What interventions are being tested in trial NCT02194049?

The interventions under investigation include: cisplatin (DRUG), etoposide (DRUG), BKM120 (DRUG).

Who is sponsoring clinical trial NCT02194049?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.