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NCT02189252 · ClinicalTrials.gov registry record · Phase 1

An Open-Label Crossover Study to Compare the Relative Bioavailability, Efficacy and Safety of Epanova® and Lovaza® in Men and Women With a History of Pancreatitis

A Phase 1 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target

NCT02189252: Completed Phase 1 study, sponsored by AstraZeneca.

NCT02189252 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02189252, a Phase 1 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

This is a randomized, open-label crossover study. The primary objective of this study is to compare the relative bioavailability of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), and the ethyl esters of EPA and DHA in plasma from a single 2 g or 4 g dose of Epanova® or 4 g Lovaza®.

Primary Outcome

AUC0-24: Area under the plasma concentration versus time curve, from time 0 to 24 hours after start of the meal

Interventions

  • DRUG Lovaza
  • DRUG Epanova

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2014-10
Est. Completion 2015-07
Phase Phase 1
AstraZeneca

1,285 total trials

What the finished NCT02189252 record still lists

NCT02189252 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 2 interventions - of which Lovaza is the first listed.

NCT02189252 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02189252 about?

NCT02189252 is a clinical study titled "An Open-Label Crossover Study to Compare the Relative Bioavailability, Efficacy and Safety of Epanova® and Lovaza® in Men and Women With a History of Pancreatitis". This is a randomized, open-label crossover study. The primary objective of this study is to compare the relative bioavailability of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), and the ethyl esters of EPA and DHA in plasma from a single 2 g or 4 g dose of Epa...

What is the current status of trial NCT02189252?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2014-10. Estimated completion is 2015-07.

What interventions are being tested in trial NCT02189252?

The interventions under investigation include: Lovaza (DRUG), Epanova (DRUG).

Who is sponsoring clinical trial NCT02189252?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02189252's enrollment target sits among peer trials

30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02189252, the US trial registry maintained by the National Library of Medicine. NCT02189252 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.