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NCT02182687 · ClinicalTrials.gov registry record · Phase 2
Stereotactic Body Radiation Therapy (SBRT) Versus Trans-Arterial Chemoembolization (TACE) as Bridge to Liver Transplant
A Phase 2 study, sponsored by Lahey Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
NCT02182687: Completed Phase 2 study, sponsored by Lahey Clinic.
NCT02182687 is a Phase 2 study that has completed, run by Lahey Clinic. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02182687, a Phase 2 study, has completed, sponsored by Lahey Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
Study Summary
This study will compare stereotactic body radiation therapy (SBRT) to trans-arterial chemoembolization (TACE) as a bridging strategy for patients with HCC undergoing orthotopic liver transplantation. We propose that SBRT will be associated with longer time intervals between initial treatment and the need for retreatment, compared to TACE, as a "bridge" to orthotopic liver transplantation.
Primary Outcome
Time from SBRT and TACE intervention to progression was tracked for subject receiving protocol intervention. Progression is defined using Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.0), as a 20% increase in the sum of the longest diameter of target lesions, or a measurable increase in a non-target lesion, or the appearance of new lesion.
Interventions
- RADIATION Stereotactic Body Radiation Therapy (SBRT)
- PROCEDURE Trans-Arterial Chemoembolization (TACE)
- DRUG Doxorubin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2014-06 |
| Est. Completion | 2021-10 |
| Phase | Phase 2 |
What the finished NCT02182687 record still lists
NCT02182687 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 3 interventions - of which Stereotactic Body Radiation Therapy (SBRT) is the first listed.
NCT02182687 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02182687 about?
NCT02182687 is a clinical study titled "Stereotactic Body Radiation Therapy (SBRT) Versus Trans-Arterial Chemoembolization (TACE) as Bridge to Liver Transplant". This study will compare stereotactic body radiation therapy (SBRT) to trans-arterial chemoembolization (TACE) as a bridging strategy for patients with HCC undergoing orthotopic liver transplantation. We propose that SBRT will be associated with longer time intervals between initial treatment and the...
What is the current status of trial NCT02182687?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2014-06. Estimated completion is 2021-10.
What interventions are being tested in trial NCT02182687?
The interventions under investigation include: Stereotactic Body Radiation Therapy (SBRT) (RADIATION), Trans-Arterial Chemoembolization (TACE) (PROCEDURE), Doxorubin (DRUG).
Who is sponsoring clinical trial NCT02182687?
This trial is sponsored by Lahey Clinic, which has 43 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02182687's enrollment target sits among peer trials
60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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