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NCT02177786 · ClinicalTrials.gov registry record · Phase 2

Efficacy, Safety, and Tolerability of Selonsertib (GS-4997) in Participants With Diabetic Kidney Disease

A Phase 2 study, sponsored by Gilead Sciences.

Completed
Registry status
Phase 2
Development phase
334
Enrollment target

NCT02177786 is a Phase 2 study that has completed, run by Gilead Sciences. The registered enrollment target is 334 participants.

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The verdict

NCT02177786, a Phase 2 study, has completed, sponsored by Gilead Sciences.

COMPLETED
Registry status
Phase 2
Development phase
334 participants
Enrollment target

Study Summary

The primary objective of this study is to determine the effect of selonsertib (formerly GS-4997) on estimated glomerular filtration rate (eGFR) decline in participants with diabetic kidney disease (DKD). Participants will be randomized with a 1:1:1:1 allocation to receive 1 of 3 doses of selonsertib (2 mg, 6 mg, or 18 mg) or matching placebo.

Interventions

  • DRUG Selonsertib
  • DRUG Placebo to match selonsertib

Trial Details

FieldValue
Enrollment Target 334 participants
Start Date 2014-06
Est. Completion 2016-08
Phase Phase 2

Sponsor

Gilead Sciences

504 total trials

What the Registry Record Tells You About NCT02177786

The ClinicalTrials.gov registry entry for NCT02177786 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 334 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 504 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Selonsertib is the first listed.

NCT02177786 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02177786 about?

NCT02177786 is a clinical study titled "Efficacy, Safety, and Tolerability of Selonsertib (GS-4997) in Participants With Diabetic Kidney Disease". The primary objective of this study is to determine the effect of selonsertib (formerly GS-4997) on estimated glomerular filtration rate (eGFR) decline in participants with diabetic kidney disease (DKD). Participants will be randomized with a 1:1:1:1 allocation to receive 1 of 3 doses of selonsertib...

What is the current status of trial NCT02177786?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 334 participants. The study started on 2014-06. Estimated completion is 2016-08.

What interventions are being tested in trial NCT02177786?

The interventions under investigation include: Selonsertib (DRUG), Placebo to match selonsertib (DRUG).

Who is sponsoring clinical trial NCT02177786?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.