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NCT02168673 · ClinicalTrials.gov registry record
Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke
A clinical trial, sponsored by Weill Medical College of Cornell University.
- Completed
- Registry status
- 1
- Enrollment target
NCT02168673: Completed study, sponsored by Weill Medical College of Cornell University.
NCT02168673 is a clinical trial that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 1 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02168673 has completed, sponsored by Weill Medical College of Cornell University.
- COMPLETED
- Registry status
- 1 participants
- Enrollment target
Study Summary
Cigarette smoking is the major risk factor for developing chronic obstructive pulmonary disease (COPD). Patients with COPD have difficulty clearing mucus and debris from their airways. Even smokers who have not developed COPD may have difficulty clearing the airways. This is partly because smoking impairs the function of cilia, tiny hairs lining the airways that sweep out mucus to keep the airways clean. The investigators have found that smoking reduces the length of cilia, which may contribute to the worsened cilia function in smoking and COPD. This is true even in smokers who show no signs of lung disease. The investigators believe that smoking affects levels of genes in lung cells, resulting in shorter cilia.
Primary Outcome
Cilia length will be measured using three preparation techniques: air-dried cytospins, detached cilia on cytospins, and mounted hydrated aliquots of cells.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2011-04 |
| Est. Completion | 2015-04 |
What the finished NCT02168673 record still lists
NCT02168673 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 1 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02168673 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02168673 about?
NCT02168673 is a clinical study titled "Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke". Cigarette smoking is the major risk factor for developing chronic obstructive pulmonary disease (COPD). Patients with COPD have difficulty clearing mucus and debris from their airways. Even smokers who have not developed COPD may have difficulty clearing the airways. This is partly because smoking i...
What is the current status of trial NCT02168673?
This trial is currently completed. The enrollment target is 1 participants. The study started on 2011-04. Estimated completion is 2015-04.
Who is sponsoring clinical trial NCT02168673?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
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