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NCT02165293 · ClinicalTrials.gov registry record · Phase 1

A Single Center Study to Evaluate the Penetration of RO7033877 Into the Lung in Healthy Volunteers

A Phase 1 study, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 1
Development phase
32
Enrollment target

NCT02165293 is a Phase 1 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 32 participants.

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The verdict

NCT02165293, a Phase 1 study, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 1
Development phase
32 participants
Enrollment target

Study Summary

This single-center, open-label study will investigate RO7033877 concentrations in plasma and in various lung compartments, including epithelial lining fluid (ELF), and alveolar macrophages (AM) in healthy volunteers after multiple intravenous (IV) administration. Bronchoscopy will be performed after the start of the last infusion on Day 3 at different timepoints. Blood, urine and brochoalveolar lavage samples will be collected to determine RO7033877 concentrations. The anticipated time on study treatment is 3 days.

Interventions

  • DRUG RO7033877 + Bronchoscopy

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2014-06
Est. Completion 2014-09
Phase Phase 1

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT02165293

The ClinicalTrials.gov registry entry for NCT02165293 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which RO7033877 + Bronchoscopy is the first listed.

NCT02165293 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02165293 about?

NCT02165293 is a clinical study titled "A Single Center Study to Evaluate the Penetration of RO7033877 Into the Lung in Healthy Volunteers". This single-center, open-label study will investigate RO7033877 concentrations in plasma and in various lung compartments, including epithelial lining fluid (ELF), and alveolar macrophages (AM) in healthy volunteers after multiple intravenous (IV) administration. Bronchoscopy will be performed after...

What is the current status of trial NCT02165293?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2014-06. Estimated completion is 2014-09.

What interventions are being tested in trial NCT02165293?

The interventions under investigation include: RO7033877 + Bronchoscopy (DRUG).

Who is sponsoring clinical trial NCT02165293?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.