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NCT02165293 · ClinicalTrials.gov registry record · Phase 1
A Single Center Study to Evaluate the Penetration of RO7033877 Into the Lung in Healthy Volunteers
A Phase 1 study, sponsored by Hoffmann-La Roche.
- Completed
- Registry status
- Phase 1
- Development phase
- 32
- Enrollment target
NCT02165293: Completed Phase 1 study, sponsored by Hoffmann-La Roche.
NCT02165293 is a Phase 1 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 32 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02165293, a Phase 1 study, has completed, sponsored by Hoffmann-La Roche.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 32 participants
- Enrollment target
Study Summary
This single-center, open-label study will investigate RO7033877 concentrations in plasma and in various lung compartments, including epithelial lining fluid (ELF), and alveolar macrophages (AM) in healthy volunteers after multiple intravenous (IV) administration. Bronchoscopy will be performed after the start of the last infusion on Day 3 at different timepoints. Blood, urine and brochoalveolar lavage samples will be collected to determine RO7033877 concentrations. The anticipated time on study treatment is 3 days.
Interventions
- DRUG RO7033877 + Bronchoscopy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2014-06 |
| Est. Completion | 2014-09 |
| Phase | Phase 1 |
What the finished NCT02165293 record still lists
NCT02165293 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 1 intervention - of which RO7033877 + Bronchoscopy is the first listed.
NCT02165293 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02165293 about?
NCT02165293 is a clinical study titled "A Single Center Study to Evaluate the Penetration of RO7033877 Into the Lung in Healthy Volunteers". This single-center, open-label study will investigate RO7033877 concentrations in plasma and in various lung compartments, including epithelial lining fluid (ELF), and alveolar macrophages (AM) in healthy volunteers after multiple intravenous (IV) administration. Bronchoscopy will be performed after...
What is the current status of trial NCT02165293?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2014-06. Estimated completion is 2014-09.
What interventions are being tested in trial NCT02165293?
The interventions under investigation include: RO7033877 + Bronchoscopy (DRUG).
Who is sponsoring clinical trial NCT02165293?
This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02165293's enrollment target sits among peer trials
32 1296th of 2000 higher than 679 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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