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NCT02156908 · ClinicalTrials.gov registry record · Phase 2

D-serine and Cognitive Remediation in Schizophrenia

A Phase 2 study, sponsored by Nathan Kline Institute for Psychiatric Research.

Completed
Registry status
Phase 2
Development phase
8
Enrollment target

NCT02156908: Completed Phase 2 study, sponsored by Nathan Kline Institute for Psychiatric Research.

NCT02156908 is a Phase 2 study that has completed, run by Nathan Kline Institute for Psychiatric Research. The registered enrollment target is 8 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02156908, a Phase 2 study, has completed, sponsored by Nathan Kline Institute for Psychiatric Research.

COMPLETED
Registry status
Phase 2
Development phase
8 participants
Enrollment target

Study Summary

The investigators will test the effects of 3 days of D-serine (DSR) on auditory plasticity in a sensory based remediation (SBR) paradigm

Primary Outcome

An MMN event is evoked by a discernible change in the pitch of a repetitive auditory stimulation. The stronger the response to a difference (i.e., the more negative the amplitude of the MMN), the better the outcome. MMN was obtained to pitch deviant stimuli pre-post auditory plasticity training, utilizing deviants to the same base frequencies as the auditory plasticity sessions, (i.e. 500, 1000, and 2000 Hz), with \~10 minutes of each base frequency. MMN will be conducted at baseline and after

Interventions

  • DRUG D-serine

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2014-08
Est. Completion 2015-12
Phase Phase 2

What the finished NCT02156908 record still lists

NCT02156908 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 1 intervention - of which D-serine is the first listed.

NCT02156908 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02156908 about?

NCT02156908 is a clinical study titled "D-serine and Cognitive Remediation in Schizophrenia". The investigators will test the effects of 3 days of D-serine (DSR) on auditory plasticity in a sensory based remediation (SBR) paradigm

What is the current status of trial NCT02156908?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2014-08. Estimated completion is 2015-12.

What interventions are being tested in trial NCT02156908?

The interventions under investigation include: D-serine (DRUG).

Who is sponsoring clinical trial NCT02156908?

This trial is sponsored by Nathan Kline Institute for Psychiatric Research, which has 20 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02156908's enrollment target sits among peer trials

8 1990th of 2000 higher than 5 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02156908, the US trial registry maintained by the National Library of Medicine. NCT02156908 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.