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NCT02154685 · ClinicalTrials.gov registry record · NA
Extinction Updating in Reconsolidation
A NA study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- NA
- Development phase
- 77
- Enrollment target
NCT02154685 is a NA study that has completed, run by Medical University of South Carolina. The registered enrollment target is 77 participants.
The verdict
NCT02154685, a NA study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- NA
- Development phase
- 77 participants
- Enrollment target
Study Summary
Smoking occurs in approximately 21% of the US population, is responsible for an annual mortality rate of approximately 438,000 citizens, and has an associated healthcare economic burden of $167 billion. Although pharmacotherapies have improved cessation outcome, the vast majority of individuals making quit attempts relapse within 5-10 days of cessation. The hypotheses to be examined in this study may have potentially important implications for smoking cessation treatment and will, therefore, target the single greatest addiction-related cause of morbidity and mortality.This study will investigate a novel behavioral strategy for altering important memory processes that underlie human smoking-related nicotine addiction. This strategy used in this study employs established cue exposure procedures to putatively update smoking-related memory with information that will suppress responding to smoking cues. The goal here is to alter existing nicotine-related memory directly rather than rely exclusively on the establishment of an inhibitory extinction process, via traditional cue exposure therapy, which is known to be vulnerable to spontaneous recovery, renewal and reinstatement. Positive findings would represent a significant advance in exposure-based therapy for addiction and could lead to a treatment that uniquely targets the problem of cue-elicited craving and reactivity, thereby addressing a major obstacle to successful smoking cessation.
Interventions
- BEHAVIORAL Retrieval-Extinction
- BEHAVIORAL Non-Retrieval Extinction
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 77 participants |
| Start Date | 2013-12 |
| Est. Completion | 2015-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02154685
The ClinicalTrials.gov registry entry for NCT02154685 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 77 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Retrieval-Extinction is the first listed.
NCT02154685 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02154685 about?
NCT02154685 is a clinical study titled "Extinction Updating in Reconsolidation". Smoking occurs in approximately 21% of the US population, is responsible for an annual mortality rate of approximately 438,000 citizens, and has an associated healthcare economic burden of $167 billion. Although pharmacotherapies have improved cessation outcome, the vast majority of individuals maki...
What is the current status of trial NCT02154685?
This trial is currently completed. It is a NA study. The enrollment target is 77 participants. The study started on 2013-12. Estimated completion is 2015-09.
What interventions are being tested in trial NCT02154685?
The interventions under investigation include: Retrieval-Extinction (BEHAVIORAL), Non-Retrieval Extinction (BEHAVIORAL).
Who is sponsoring clinical trial NCT02154685?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
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