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NCT02142543 · ClinicalTrials.gov registry record · Early Phase 1
The Effect of 2-DeNT Oral Topical Powder on Minor Recurrent Aphthous Ulcer
A Early Phase 1 study of Minor Recurrent Aphthous Stomatitis Lesions, sponsored by Texas A&M University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 23
- Enrollment target
- 1
- Study location
NCT02142543: Completed Early Phase 1 study of Minor Recurrent Aphthous Stomatitis Lesions, sponsored by Texas A&M University.
NCT02142543 is a Early Phase 1 study of Minor Recurrent Aphthous Stomatitis Lesions that has completed, run by Texas A&M University. The registered enrollment target is 23 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02142543, a Early Phase 1 study of Minor Recurrent Aphthous Stomatitis Lesions, has completed, sponsored by Texas A&M University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 23 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective, randomized, blinded, placebo-controlled, crossover clinical trial to evaluate the efficacy of 2-DeNT oral topical powder in the treatment of recurrent aphthous stomatitis (RAS). To be included in the study, subjects must have had minor RAS ulcers of less than 48 hours duration. It was randomly determined which powder was used first; all subjects used both the 2-DeNT powder and the placebo powder. Subjects applied the powder twice daily and maintained a daily log recording the size of the ulcer, its erythema score, and their level of pain. The subjects continued applying the 2-DeNT powder until the ulcer was resolved.
Primary Outcome
Size was measured from the outside edge of the white border to the outside edge of the opposite white border. If the ulcer was oval in shape, its longest dimension was measured.
Conditions Studied
Interventions
- DRUG Placebo Comparator
- DRUG 2-DeNT powder
Study Locations (1)
Texas
- Texas A&M Baylor College of Dentisry - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2012-03 |
| Est. Completion | 2012-12 |
| Phase | Early Phase 1 |
What the finished NCT02142543 record still lists
NCT02142543 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (57% lower).
The record links to 1 condition, with Minor Recurrent Aphthous Stomatitis Lesions appearing as the primary indexed condition, and to 2 interventions - of which Placebo Comparator is the first listed.
NCT02142543 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT02142543 about?
NCT02142543 is a clinical study titled "The Effect of 2-DeNT Oral Topical Powder on Minor Recurrent Aphthous Ulcer". This is a prospective, randomized, blinded, placebo-controlled, crossover clinical trial to evaluate the efficacy of 2-DeNT oral topical powder in the treatment of recurrent aphthous stomatitis (RAS). To be included in the study, subjects must have had minor RAS ulcers of less than 48 hours duration...
What is the current status of trial NCT02142543?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 23 participants. The study started on 2012-03. Estimated completion is 2012-12.
What conditions does trial NCT02142543 study?
This clinical trial studies the following conditions: Minor Recurrent Aphthous Stomatitis Lesions.
What interventions are being tested in trial NCT02142543?
The interventions under investigation include: Placebo Comparator (DRUG), 2-DeNT powder (DRUG).
Who is sponsoring clinical trial NCT02142543?
This trial is sponsored by Texas A&M University, which has 95 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02142543 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02142543's enrollment target sits among peer trials
23 1088th of 2000 higher than 898 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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