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NCT02131324 · ClinicalTrials.gov registry record · Phase 2
DFD06 Cream vs Clobetasol Propionate Cream, 0.05% Hypothalamic- Pituitary-Adrenal (HPA) Axis Suppression Study in Patients With Moderate to Severe Plaque Psoriasis
A Phase 2 study, sponsored by Promius Pharma.
- Completed
- Registry status
- Phase 2
- Development phase
- 50
- Enrollment target
NCT02131324: Completed Phase 2 study, sponsored by Promius Pharma.
NCT02131324 is a Phase 2 study that has completed, run by Promius Pharma. The registered enrollment target is 50 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02131324, a Phase 2 study, has completed, sponsored by Promius Pharma.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 50 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the potential of DFD06 cream to suppress the HPA (hypothalamic-pituitary-adrenal) axis as compared to clobetasol propionate cream, 0.05% cream when applied twice daily for 15 days.
Primary Outcome
HPA axis suppression as measured by serum cortisol levels post cosyntropin test (ACTH test)
Interventions
- DRUG DFD06 Cream
- DRUG Clobetasol Propionate Cream 0.05%
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2014-05-08 |
| Est. Completion | 2016-08-11 |
| Phase | Phase 2 |
What the finished NCT02131324 record still lists
NCT02131324 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 2 interventions - of which DFD06 Cream is the first listed.
NCT02131324 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02131324 about?
NCT02131324 is a clinical study titled "DFD06 Cream vs Clobetasol Propionate Cream, 0.05% Hypothalamic- Pituitary-Adrenal (HPA) Axis Suppression Study in Patients With Moderate to Severe Plaque Psoriasis". The purpose of this study is to evaluate the potential of DFD06 cream to suppress the HPA (hypothalamic-pituitary-adrenal) axis as compared to clobetasol propionate cream, 0.05% cream when applied twice daily for 15 days.
What is the current status of trial NCT02131324?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2014-05-08. Estimated completion is 2016-08-11.
What interventions are being tested in trial NCT02131324?
The interventions under investigation include: DFD06 Cream (DRUG), Clobetasol Propionate Cream 0.05% (DRUG).
Who is sponsoring clinical trial NCT02131324?
This trial is sponsored by Promius Pharma, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02131324's enrollment target sits among peer trials
50 1195th of 2000 higher than 740 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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