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NCT02131116 · ClinicalTrials.gov registry record · NA

Integrated Metacognitive Therapy in First Episode Psychosis

A NA study, sponsored by Indiana University.

Completed
Registry status
NA
Development phase
20
Enrollment target

NCT02131116 is a NA study that has completed, run by Indiana University. The registered enrollment target is 20 participants.

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The verdict

NCT02131116, a NA study, has completed, sponsored by Indiana University.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

Insight, or lack of illness awareness, is a prominent and pressing clinical concern in the treatment and recovery of patients with psychotic disorders. Impaired insight results in poor treatment engagement and adherence, more frequent hospitalizations, greater positive and negative symptoms, and poor psychosocial functioning. Addressing these complications early in the disease process may lead to altered illness course with better outcomes. To date, only a small number of nonpharmacological interventions have been developed, none of which adequately address poor insight during the first few years of psychotic illness. Further, presently available therapeutic interventions do not attend to difficulties associated with improved insight, such as depression. The purpose of this investigation is to implement a novel intervention designed to improve insight, metacognition, neurocognition, symptoms, and ultimately overall functioning in persons with early psychosis. The novel intervention will integrate a number of previously established therapeutic approaches, such as metacognitive, narrative, cognitive behavioral and motivational interviewing, and hence be labeled Integrated Metacognitive Therapy (IMT). In order to measure the efficacy of IMT, all subjects will undergo a battery of assessments in each of these domains prior to and following either a novel intervention (N = 10) or treatment as usual (N = 10) for a period of approximately six months. Throughout the study, each IMT session (N = 10, 24 sessions each) will be audio recorded, transcribed, and de-identified to allow for careful ongoing qualitative analyses of potential active and inert ingredients of the approach and ultimately the development of an IMT manual which can then be tested in a larger, more rigorous randomized control trial. This investigation will play an important role in advancing current knowledge about treating insight in early psychosis. Further, it will serve to expand upon the intervention t

Interventions

  • BEHAVIORAL Treatment as Usual
  • BEHAVIORAL Integrated Metacognitive Therapy

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2014-05
Est. Completion 2017-12
Phase NA

Sponsor

Indiana University

890 total trials

What the Registry Record Tells You About NCT02131116

The ClinicalTrials.gov registry entry for NCT02131116 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Treatment as Usual is the first listed.

NCT02131116 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02131116 about?

NCT02131116 is a clinical study titled "Integrated Metacognitive Therapy in First Episode Psychosis". Insight, or lack of illness awareness, is a prominent and pressing clinical concern in the treatment and recovery of patients with psychotic disorders. Impaired insight results in poor treatment engagement and adherence, more frequent hospitalizations, greater positive and negative symptoms, and poo...

What is the current status of trial NCT02131116?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2014-05. Estimated completion is 2017-12.

What interventions are being tested in trial NCT02131116?

The interventions under investigation include: Treatment as Usual (BEHAVIORAL), Integrated Metacognitive Therapy (BEHAVIORAL).

Who is sponsoring clinical trial NCT02131116?

This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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