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NCT02119455 · ClinicalTrials.gov registry record · NA
Biomarkers of Orthodontic Tooth Movement With Fixed Appliances and Vibration Appliance Therapy
A NA study, sponsored by UConn Health.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT02119455: Completed NA study, sponsored by UConn Health.
NCT02119455 is a NA study that has completed, run by UConn Health. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02119455, a NA study, has completed, sponsored by UConn Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
Currently, orthodontic treatment typically lasts approximately 2 years. There are a number of advantages for reducing the duration of treatment, including reducing the potential risk of caries, root resorption and for minimizing patient "burn out" from prolonged treatment. While some evidence does exist that vibration may accelerate the speed of tooth movement, the biological mechanism is still unknown. Identification of specific factors involved in tooth movement that are further stimulated by vibration would help to understand the mechanisms involved as well as discover possible biologic targets which could be utilized or modified to maximize the benefits of vibration treatment. The purpose of this study is to identify novel biological factors that are expressed in patients undergoing orthodontic tooth movement in conjunction with vibration appliance therapy.
Primary Outcome
Saliva will be collected as T0 (Baseline), T1 (5-6 weeks), T2 (10-12 weeks), T3 (15-17 weeks). Saliva will be analysed for a variety of biomarkers with protein quantified by ELISA assay at each time point for each subject.
Interventions
- DEVICE Vibration Device
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2014-04 |
| Est. Completion | 2018-06 |
| Phase | NA |
What the finished NCT02119455 record still lists
NCT02119455 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Vibration Device is the first listed.
NCT02119455 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02119455 about?
NCT02119455 is a clinical study titled "Biomarkers of Orthodontic Tooth Movement With Fixed Appliances and Vibration Appliance Therapy". Currently, orthodontic treatment typically lasts approximately 2 years. There are a number of advantages for reducing the duration of treatment, including reducing the potential risk of caries, root resorption and for minimizing patient "burn out" from prolonged treatment. While some evidence does ...
What is the current status of trial NCT02119455?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2014-04. Estimated completion is 2018-06.
What interventions are being tested in trial NCT02119455?
The interventions under investigation include: Vibration Device (DEVICE).
Who is sponsoring clinical trial NCT02119455?
This trial is sponsored by UConn Health, which has 178 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02119455's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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