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NCT02115685 · ClinicalTrials.gov registry record · NA
Sympathetic-Somatomotor Coupling in Human Spinal Cord Injury
A NA study, sponsored by Shirley Ryan AbilityLab.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT02115685: Completed NA study, sponsored by Shirley Ryan AbilityLab.
NCT02115685 is a NA study that has completed, run by Shirley Ryan AbilityLab. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02115685, a NA study, has completed, sponsored by Shirley Ryan AbilityLab.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
Significance: The long term objective of this study is to improve physical therapy and fitness programs in people with spinal cord injury. The results of the study will demonstrate the importance of matching blood flow to a muscle with exercise of that same muscle. Scientific Objective: The objective of the study is to measure how the body regulates bloodflow to a muscle during exercise. We intend to study these effects by triggering blood flow changes during movement, and measuring bloodflow changes during exercise in people with spinal cord injury. We will also look at the long term effects of different exercise programs on bloodflow during exercise. Study Populations: This study will involve people with partial spinal cord injury and age and sex matched controls without injury. Specific Aims: Aim 1 will be to measure bloodflow during exercise of the legs (below the injury). This aim will examine the control of bloodflow and muscle contractions and how it changes after spinal cord injury. Aim 2 will then look at changes in bloodflow during exercise after training. Three different eight week exercise training programs will be tested including 1) upper body ergometry, 2) treadmill training with exertion level matched to the upper body ergometry and 3) treadmill training with heart rate matched to an initial test of upper body ergometry.
Primary Outcome
Subject will be tested with doppler ultrasonography immediately pre and post sympathetic stressor. Testing sessions will take anywhere between 3-6 hours.
Interventions
- OTHER Treadmill Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2014-04 |
| Est. Completion | 2020-04 |
| Phase | NA |
What the finished NCT02115685 record still lists
NCT02115685 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Treadmill Training is the first listed.
NCT02115685 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02115685 about?
NCT02115685 is a clinical study titled "Sympathetic-Somatomotor Coupling in Human Spinal Cord Injury". Significance: The long term objective of this study is to improve physical therapy and fitness programs in people with spinal cord injury. The results of the study will demonstrate the importance of matching blood flow to a muscle with exercise of that same muscle. Scientific Objective: The objecti...
What is the current status of trial NCT02115685?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2014-04. Estimated completion is 2020-04.
What interventions are being tested in trial NCT02115685?
The interventions under investigation include: Treadmill Training (OTHER).
Who is sponsoring clinical trial NCT02115685?
This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02115685's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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