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NCT02114697 · ClinicalTrials.gov registry record · Phase 4
Accelerated Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging
A Phase 4 study, sponsored by Emory University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 9
- Enrollment target
NCT02114697: Clinical Trial Phase 4 study, sponsored by Emory University.
NCT02114697 is a Phase 4 study that was terminated before completion, run by Emory University. The registered enrollment target is 9 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02114697, a Phase 4 study, was terminated before completion, sponsored by Emory University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 9 participants
- Enrollment target
Study Summary
The goal of this study is to assess a slimy substance that settles/deposits along blood vessel wall. This slimy substance is called plaque. Plaque could be made up of fat, calcium or both. Plaque deposition narrows the vessels. This leads to decreased blood flow to various parts of body. Blood vessels include vessels that supply to heart (coronary), vessels to brain (carotid), vessels to kidneys (renal) and vessels to legs (femoral). Decreased blood flow causes symptoms such as brain stroke, heart attack, leg pain. Similarly individuals at risk of cardiovascular disease can have certain markers elevated in their blood that can be measured by simple blood tests. High or increased plaque deposition is seen in neck vessels of cancer patients who received radiation to chest or head and neck as part of their cancer treatment. Cancer survivors are at increased risk of plaque development and are therefore called high-risk population. Exercise +/- fat lowering medicine can potentially decrease plaque deposition and statins are one of the several fat lowering medications.
Primary Outcome
Plaque volume of carotid arteries were measured by MRI as a surrogate for progression of cardiovascular disease. Plaque volume varies with observed ranges from other studies ranging from 23.9 to 604.1mm\^3. Plaque volume tends to increase with age. Increased plaque volume has an increased risk of vascular events.
Interventions
- BEHAVIORAL Lifestyle modification
- DRUG Statin therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2014-04 |
| Est. Completion | 2017-07 |
| Phase | Phase 4 |
Why NCT02114697 stopped before completion
NCT02114697 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Lifestyle modification is the first listed.
NCT02114697 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02114697 about?
NCT02114697 is a clinical study titled "Accelerated Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging". The goal of this study is to assess a slimy substance that settles/deposits along blood vessel wall. This slimy substance is called plaque. Plaque could be made up of fat, calcium or both. Plaque deposition narrows the vessels. This leads to decreased blood flow to various parts of body. Blood vesse...
What is the current status of trial NCT02114697?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 9 participants. The study started on 2014-04. Estimated completion is 2017-07.
What interventions are being tested in trial NCT02114697?
The interventions under investigation include: Lifestyle modification (BEHAVIORAL), Statin therapy (DRUG).
Who is sponsoring clinical trial NCT02114697?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02114697's enrollment target sits among peer trials
9 1968th of 2000 higher than 29 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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