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NCT02113449 · ClinicalTrials.gov registry record · Phase 2

Market Potential of Carbon Dioxide Nasal Spray

A Phase 2 study, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 2
Development phase
147
Enrollment target

NCT02113449: Completed Phase 2 study, sponsored by GlaxoSmithKline.

NCT02113449 is a Phase 2 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 147 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (11% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02113449, a Phase 2 study, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 2
Development phase
147 participants
Enrollment target

Study Summary

Carbon dioxide (CO2) is a naturally occurring gas that readily diffuses across body tissues and membranes. Data from earlier clinical studies conducted in 975 subjects with allergic rhinitis have shown that nasally administered CO2 may provide relief of the associated symptoms. Symptom relief has been shown to occur as soon as 10 minutes after administration, and may persist for four to six hours. This study aims to assess the consumer appeal of a prototype CO2 delivery device, as well as evaluate its perceived effectiveness for nasal congestion. Properly consented subjects who qualify and choose to participate in the clinical study will be administered nasal CO2 under medical supervision, wait a period of 1 hour in clinic, and then be dispensed a device for self-treatment at home. Subjects will return to the clinic on day 7 for final evaluation and completion of assessment questionnaires.

Primary Outcome

There was one questionnaire used in this study which was divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked as part of screening survey prior to concept viewing. If the participant answered "I do not purchase any product to relieve congestion" the participant was excluded. Participants could select only one option available.

Interventions

  • DRUG Carbon Dioxide

Trial Details

FieldValue
Enrollment Target 147 participants
Start Date 2013-11
Est. Completion 2014-02
Phase Phase 2
GlaxoSmithKline

1,345 total trials

What the finished NCT02113449 record still lists

NCT02113449 is an interventional study that assigns participants to a tested intervention. The registered 147 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (11% higher).

The record links to 0 conditions, and to 1 intervention - of which Carbon Dioxide is the first listed.

NCT02113449 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02113449 about?

NCT02113449 is a clinical study titled "Market Potential of Carbon Dioxide Nasal Spray". Carbon dioxide (CO2) is a naturally occurring gas that readily diffuses across body tissues and membranes. Data from earlier clinical studies conducted in 975 subjects with allergic rhinitis have shown that nasally administered CO2 may provide relief of the associated symptoms. Symptom relief has be...

What is the current status of trial NCT02113449?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 147 participants. The study started on 2013-11. Estimated completion is 2014-02.

What interventions are being tested in trial NCT02113449?

The interventions under investigation include: Carbon Dioxide (DRUG).

Who is sponsoring clinical trial NCT02113449?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02113449's enrollment target sits among peer trials

147 495th of 2000 higher than 1,505 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02113449, the US trial registry maintained by the National Library of Medicine. NCT02113449 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.