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NCT02113215 · ClinicalTrials.gov registry record
Very Low Density Lipoprotein Turnover in Young and Elderly Individuals
A clinical trial, sponsored by The University of Texas Medical Branch, Galveston.
- Terminated
- Registry status
- 24
- Enrollment target
NCT02113215: Clinical Trial study, sponsored by The University of Texas Medical Branch, Galveston.
NCT02113215 is a clinical trial that was terminated before completion, run by The University of Texas Medical Branch, Galveston. The registered enrollment target is 24 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02113215 was terminated before completion, sponsored by The University of Texas Medical Branch, Galveston.
- TERMINATED
- Registry status
- 24 participants
- Enrollment target
Study Summary
Intrahepatic and intramyocellular lipid concentrations are elevated in elderly individuals relative to young people, despite no significant difference in fasting plasma TAG concentrations. Our general hypothesis is that the increase in intrahepatic fat with age results from reduced VLDL turnover, and therefore elderly individuals in this study will display lower VLDL turnover rates than young individuals. The aims of this study are a) to compare VLDL turnover in young and elderly individuals, and b) to compare a bolus method and a constant infusion method of assessing VLDL turnover.
Primary Outcome
Turnover rates of VLDL-triglycerides and VLDL-ApoB (apolipoprotein B)-100, including synthesis and breakdown rates, measured during a 9-hour infusion trial.
Interventions
- PROCEDURE Stable Isotope Infusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2011-12 |
| Est. Completion | 2013-07 |
Why NCT02113215 stopped before completion
NCT02113215 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 24 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Stable Isotope Infusion is the first listed.
NCT02113215 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02113215 about?
NCT02113215 is a clinical study titled "Very Low Density Lipoprotein Turnover in Young and Elderly Individuals". Intrahepatic and intramyocellular lipid concentrations are elevated in elderly individuals relative to young people, despite no significant difference in fasting plasma TAG concentrations. Our general hypothesis is that the increase in intrahepatic fat with age results from reduced VLDL turnover, an...
What is the current status of trial NCT02113215?
This trial is currently terminated. The enrollment target is 24 participants. The study started on 2011-12. Estimated completion is 2013-07.
What interventions are being tested in trial NCT02113215?
The interventions under investigation include: Stable Isotope Infusion (PROCEDURE).
Who is sponsoring clinical trial NCT02113215?
This trial is sponsored by The University of Texas Medical Branch, Galveston, which has 203 total clinical trials registered on ClinicalTrials.gov.
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