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NCT02109848 · ClinicalTrials.gov registry record
Observational Study of Keratoconus and Post-keratoplasty Eyes
A clinical trial, sponsored by Oregon Health and Science University.
- Completed
- Registry status
- 7
- Enrollment target
NCT02109848: Completed study, sponsored by Oregon Health and Science University.
NCT02109848 is a clinical trial that has completed, run by Oregon Health and Science University. The registered enrollment target is 7 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02109848 has completed, sponsored by Oregon Health and Science University.
- COMPLETED
- Registry status
- 7 participants
- Enrollment target
Study Summary
A prospective observational study on keratoconus and post-keratoplasty will be conducted. We will enroll 50 subjects in each of 3 groups: keratoconus, post-PK, and post-DSAEK. The Optovue anterior segment OCT prototype will be used to perform 3-D corneal scans. These scans will be used to measure corneal thickness (pachymetry), corneal topography (anterior and posterior) and epithelial thickness maps. The ultrahigh-speed MIT OCT prototypes will also be used when they become available. A comprehensive eye examination, Placido-ring corneal topography, ultrasound pachymetry, and Scheimpflug camera imagery, will be performed for comparison. In some post-PK and post-DSAEK cases, vision will be primarily affected by regular astigmatism, myopia, or hyperopia, rather than HOA. These cases can be corrected by standard PRK (not OCT guided) with adjunctive mitomycin C treatment to prevent haze formation.107, 108 In these cases PRK will be performed according to the standard of care and will not be a part of the study protocol. The postoperative results will be observed at the 3-4 month visit with UCVA, manifest refraction, BSCVA, OCT scanning, Placido topography, ultrasound pachymetry, and Scheimpflug camera imagery
Primary Outcome
The primary goal of this observational study is to validate OCT anterior topography by comparison with standard Placido-ring corneal topography
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2011-06 |
| Est. Completion | 2017-08-31 |
What the finished NCT02109848 record still lists
NCT02109848 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 7 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02109848 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02109848 about?
NCT02109848 is a clinical study titled "Observational Study of Keratoconus and Post-keratoplasty Eyes". A prospective observational study on keratoconus and post-keratoplasty will be conducted. We will enroll 50 subjects in each of 3 groups: keratoconus, post-PK, and post-DSAEK. The Optovue anterior segment OCT prototype will be used to perform 3-D corneal scans. These scans will be used to measure co...
What is the current status of trial NCT02109848?
This trial is currently completed. The enrollment target is 7 participants. The study started on 2011-06. Estimated completion is 2017-08-31.
Who is sponsoring clinical trial NCT02109848?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
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