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NCT02100748 · ClinicalTrials.gov registry record · Phase 2
A Study of TRV130 for the Treatment of Pain After Bunionectomy
A Phase 2 study, sponsored by Trevena.
- Completed
- Registry status
- Phase 2
- Development phase
- 333
- Enrollment target
NCT02100748: Completed Phase 2 study, sponsored by Trevena.
NCT02100748 is a Phase 2 study that has completed, run by Trevena. The registered enrollment target is 333 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (150% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02100748, a Phase 2 study, has completed, sponsored by Trevena.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 333 participants
- Enrollment target
Study Summary
The primary objective is to evaluate the analgesic efficacy of IV TRV130 compared with placebo in patients with acute postoperative pain after bunionectomy.
Primary Outcome
Pain intensity will be evaluated using an 11-point (0-10) Numeric Pain Rating Scale (NPRS), with higher numbers indicating a higher pain intensity, administered over 48 hours. Time weighted average change from baseline is calculated using the following: time weighted sum of pain intensity differences (SPID) divided by a constant (48 hours) to yield values on the 0-10 NPRS.
Interventions
- DRUG Placebo
- DRUG Morphine
- DRUG TRV130
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 333 participants |
| Start Date | 2014-04 |
| Est. Completion | 2014-10 |
| Phase | Phase 2 |
What the finished NCT02100748 record still lists
NCT02100748 is an interventional study that assigns participants to a tested intervention. The registered 333 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (150% higher).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT02100748 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02100748 about?
NCT02100748 is a clinical study titled "A Study of TRV130 for the Treatment of Pain After Bunionectomy". The primary objective is to evaluate the analgesic efficacy of IV TRV130 compared with placebo in patients with acute postoperative pain after bunionectomy.
What is the current status of trial NCT02100748?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 333 participants. The study started on 2014-04. Estimated completion is 2014-10.
What interventions are being tested in trial NCT02100748?
The interventions under investigation include: Placebo (DRUG), Morphine (DRUG), TRV130 (DRUG).
Who is sponsoring clinical trial NCT02100748?
This trial is sponsored by Trevena, which has 15 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02100748's enrollment target sits among peer trials
333 144th of 2000 higher than 1,857 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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