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NCT02093962 · ClinicalTrials.gov registry record · Phase 2

Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer

A Phase 2 study, sponsored by ImmunoGenesis.

Terminated
Registry status
Phase 2
Development phase
265
Enrollment target

NCT02093962: Clinical Trial Phase 2 study, sponsored by ImmunoGenesis.

NCT02093962 is a Phase 2 study that was terminated before completion, run by ImmunoGenesis. The registered enrollment target is 265 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (99% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02093962, a Phase 2 study, was terminated before completion, sponsored by ImmunoGenesis.

TERMINATED
Registry status
Phase 2
Development phase
265 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether TH-302 in combination with pemetrexed is safe and effective in the treatment of non-squamous non-small cell lung cancer.

Primary Outcome

To assess the efficacy of pemetrexed in combination with TH-302 as determined by overall survival in patients with advanced non-squamous NSCLC in the second-line chemotherapy setting compared with pemetrexed in combination with placebo

Interventions

  • DRUG TH-302 combination with pemetrexed
  • DRUG Matched placebo in combination with pemetrexed

Trial Details

FieldValue
Enrollment Target 265 participants
Start Date 2014-06
Est. Completion 2016-05
Phase Phase 2
ImmunoGenesis

8 total trials

Why NCT02093962 stopped before completion

NCT02093962 is an interventional study that assigns participants to a tested intervention. The registered 265 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (99% higher).

The record links to 0 conditions, and to 2 interventions - of which TH-302 combination with pemetrexed is the first listed.

NCT02093962 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02093962 about?

NCT02093962 is a clinical study titled "Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer". The purpose of this study is to determine whether TH-302 in combination with pemetrexed is safe and effective in the treatment of non-squamous non-small cell lung cancer.

What is the current status of trial NCT02093962?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 265 participants. The study started on 2014-06. Estimated completion is 2016-05.

What interventions are being tested in trial NCT02093962?

The interventions under investigation include: TH-302 combination with pemetrexed (DRUG), Matched placebo in combination with pemetrexed (DRUG).

Who is sponsoring clinical trial NCT02093962?

This trial is sponsored by ImmunoGenesis, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02093962's enrollment target sits among peer trials

265 210th of 2000 higher than 1,791 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02093962, the US trial registry maintained by the National Library of Medicine. NCT02093962 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.