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NCT02093728 · ClinicalTrials.gov registry record · Phase 1
To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
A Phase 1 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 1
- Development phase
- 26
- Enrollment target
NCT02093728: Completed Phase 1 study, sponsored by AstraZeneca.
NCT02093728 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 26 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02093728, a Phase 1 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 26 participants
- Enrollment target
Study Summary
Study to assess the effect of Itraconazole and Fluconazole on the pharmacokinetics of Selumetinib (AZD6244; ARRY-142866) ( Hyd-Sulfate) in Healthy Male Volunteers
Primary Outcome
Samples taken during each of the 6 treatments
Interventions
- DRUG itraconazole
- DRUG selumetinib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2014-04 |
| Est. Completion | 2014-06 |
| Phase | Phase 1 |
What the finished NCT02093728 record still lists
NCT02093728 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower).
The record links to 0 conditions, and to 2 interventions - of which itraconazole is the first listed.
NCT02093728 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02093728 about?
NCT02093728 is a clinical study titled "To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers". Study to assess the effect of Itraconazole and Fluconazole on the pharmacokinetics of Selumetinib (AZD6244; ARRY-142866) ( Hyd-Sulfate) in Healthy Male Volunteers
What is the current status of trial NCT02093728?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2014-04. Estimated completion is 2014-06.
What interventions are being tested in trial NCT02093728?
The interventions under investigation include: itraconazole (DRUG), selumetinib (DRUG).
Who is sponsoring clinical trial NCT02093728?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02093728's enrollment target sits among peer trials
26 1482nd of 2000 higher than 506 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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