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NCT02087943 · ClinicalTrials.gov registry record · Phase 2

Efficacy and Safety Study of Apremilast in Subjects With Moderate to Severe Atopic Dermatitis

A Phase 2 study, sponsored by Amgen.

Completed
Registry status
Phase 2
Development phase
191
Enrollment target

NCT02087943: Completed Phase 2 study, sponsored by Amgen.

NCT02087943 is a Phase 2 study that has completed, run by Amgen. The registered enrollment target is 191 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02087943, a Phase 2 study, has completed, sponsored by Amgen.

COMPLETED
Registry status
Phase 2
Development phase
191 participants
Enrollment target

Study Summary

A study to evaluate the efficacy and safety of apremilast (CC-10004) in subjects with moderate to severe atopic dermatitis

Primary Outcome

EASI is a validated composite scoring system integrating the proportion of the body region (area) involved and the intensity of key signs of atopic dermatitis (AD). A representative lesion is selected for each of the four body regions for assessing the intensity of each of the four signs (erythema, induration /papulation, excoriation, and lichenification). Symptoms (eg, pruritus) and secondary signs (eg, xerosis, scaling) are excluded from the assessment. The total EASI score ranges from 0 to 72

Interventions

  • DRUG Placebo
  • DRUG Apremilast

Trial Details

FieldValue
Enrollment Target 191 participants
Start Date 2014-06
Est. Completion 2016-02
Phase Phase 2
Amgen

558 total trials

What the finished NCT02087943 record still lists

NCT02087943 is an interventional study that assigns participants to a tested intervention. The registered 191 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02087943 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02087943 about?

NCT02087943 is a clinical study titled "Efficacy and Safety Study of Apremilast in Subjects With Moderate to Severe Atopic Dermatitis". A study to evaluate the efficacy and safety of apremilast (CC-10004) in subjects with moderate to severe atopic dermatitis

What is the current status of trial NCT02087943?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 191 participants. The study started on 2014-06. Estimated completion is 2016-02.

What interventions are being tested in trial NCT02087943?

The interventions under investigation include: Placebo (DRUG), Apremilast (DRUG).

Who is sponsoring clinical trial NCT02087943?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02087943's enrollment target sits among peer trials

191 353rd of 2000 higher than 1,648 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02087943, the US trial registry maintained by the National Library of Medicine. NCT02087943 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.