Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02085057 · ClinicalTrials.gov registry record
Neural Links Between OCD and Anorexia
A clinical trial, sponsored by Stanford University.
- Completed
- Registry status
- 64
- Enrollment target
NCT02085057: Completed study, sponsored by Stanford University.
NCT02085057 is a clinical trial that has completed, run by Stanford University. The registered enrollment target is 64 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02085057 has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- 64 participants
- Enrollment target
Study Summary
Individuals with anorexia nervosa (AN) have long been observed to demonstrate symptoms in common with obsessive-compulsive disorder (OCD), in particular, an obsessive fear of normal weight leading to dangerous food restriction, as well as many compulsive rituals about food. Both AN and OCD are seriously handicapping and often resistant to conventional therapies. Given that the two conditions often co-occur and are associated with still unknown genetic risk factors, the aim of this project is to identify their shared and distinct patterns of brain activity. The investigators propose to use functional magnetic resonance imaging to compare brain response among adolescents with AN, OCD, and age-matched healthy individuals. Specifically, this study will investigate function of distinct brain circuits related to core aspects of these related disorders. The investigators use three tasks related to set shifting, global vs. local processing, and reward. Based on evidence of deficits in cognitive flexibility and ability to change behavior, the investigators hypothesize that adolescents with AN and with OCD will show hypoactivity of frontostriatal circuitry during cognitive tasks, and adolescents with AN will show hyperactivity in limbic regions in a reward task. This study is the first to directly compare brain activation patterns using functional neuroimaging in AN and OCD. The goal is to determine how abnormal brain activity relates to symptom formation, what accounts for shared characteristics amongst these disorders, and whether deficits in specific circuitry underlie their unique defining features. The study of shared and unique elements of functional brain circuitry reflects a new, emerging approach to the classification of psychiatric illness, one based on identifying unique combinations of biological risk factors that link related conditions. This approach is widely believed to be a critical step forward in developing more brain-relevant targeted strategies for prev
Interventions
- PROCEDURE Functional Magnetic Resonance Imaging
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 64 participants |
| Start Date | 2013-01 |
| Est. Completion | 2017-04-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02085057
The ClinicalTrials.gov registry entry for NCT02085057 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 64 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Functional Magnetic Resonance Imaging is the first listed.
NCT02085057 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02085057 about?
NCT02085057 is a clinical study titled "Neural Links Between OCD and Anorexia". Individuals with anorexia nervosa (AN) have long been observed to demonstrate symptoms in common with obsessive-compulsive disorder (OCD), in particular, an obsessive fear of normal weight leading to dangerous food restriction, as well as many compulsive rituals about food. Both AN and OCD are serio...
What is the current status of trial NCT02085057?
This trial is currently completed. The enrollment target is 64 participants. The study started on 2013-01. Estimated completion is 2017-04-01.
What interventions are being tested in trial NCT02085057?
The interventions under investigation include: Functional Magnetic Resonance Imaging (PROCEDURE).
Who is sponsoring clinical trial NCT02085057?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.