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NCT02084797 · ClinicalTrials.gov registry record · NA

V2 Receptor Effects on Fluid Regulation and Performance

A NA study, sponsored by Oakland University.

Completed
Registry status
NA
Development phase
10
Enrollment target

NCT02084797: Completed NA study, sponsored by Oakland University.

NCT02084797 is a NA study that has completed, run by Oakland University. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02084797, a NA study, has completed, sponsored by Oakland University.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

This primary aim of this study was to critically assess whether or not sweat water content and sodium concentration were acutely regulated by dynamic changes in antidiuretic hormone (arginine vasopressin or AVP) acting on the Vasopressin 2 receptor (V2R) during exercise. Secondary aims were to evaluate running performance and core temperature to further characterize the role of AVP in the coordinated balance of fluid and temperature homeostasis during exercise. The primary hypothesis was that activation of the V2R in sweat glands would result in water reabsorption and fluid conservation during endurance exercise.

Primary Outcome

Changes in sweat sodium concentration will parallel changes in urine sodium concentration with use of the V2R antagonist, agonist and placebo if the primary hypothesis is true (sweat sodium is regulated by the V2R, similar to how urine sodium is regulated by principle cells located within in the kidney collecting duct)

Interventions

  • DRUG V2R (Vasopressin 2 receptor)

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2011-06
Est. Completion 2012-10
Phase NA
Oakland University

9 total trials

What the finished NCT02084797 record still lists

NCT02084797 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which V2R (Vasopressin 2 receptor) is the first listed.

NCT02084797 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02084797 about?

NCT02084797 is a clinical study titled "V2 Receptor Effects on Fluid Regulation and Performance". This primary aim of this study was to critically assess whether or not sweat water content and sodium concentration were acutely regulated by dynamic changes in antidiuretic hormone (arginine vasopressin or AVP) acting on the Vasopressin 2 receptor (V2R) during exercise. Secondary aims were to evalu...

What is the current status of trial NCT02084797?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2011-06. Estimated completion is 2012-10.

What interventions are being tested in trial NCT02084797?

The interventions under investigation include: V2R (Vasopressin 2 receptor) (DRUG).

Who is sponsoring clinical trial NCT02084797?

This trial is sponsored by Oakland University, which has 9 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02084797's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02084797, the US trial registry maintained by the National Library of Medicine. NCT02084797 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.