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NCT02081001 · ClinicalTrials.gov registry record · Phase 2

PK/PD Study With G-Pump (Glucagon Infusion) in T1DM Patients

A Phase 2 study, sponsored by Xeris Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
19
Enrollment target

NCT02081001: Completed Phase 2 study, sponsored by Xeris Pharmaceuticals.

NCT02081001 is a Phase 2 study that has completed, run by Xeris Pharmaceuticals. The registered enrollment target is 19 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02081001, a Phase 2 study, has completed, sponsored by Xeris Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
19 participants
Enrollment target

Study Summary

The purpose of the study is to assess the safety, speed of absorption, and onset of action of G-Pump™ (glucagon infusion) at three subcutaneous doses as compared to Novo GlucaGen®, all delivered via an OmniPod® infusion pump to patients with type 1 diabetes.

Primary Outcome

The onset of action was assessed by determining the time in minutes required to achieve 50% of the maximum plasma concentration of glucose following each dose of glucagon.

Interventions

  • DRUG G-Pump™ (glucagon infusion)
  • DRUG Novo Nordisk GlucaGen®

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2014-03
Est. Completion 2014-09
Phase Phase 2
Xeris Pharmaceuticals

14 total trials

What the finished NCT02081001 record still lists

NCT02081001 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).

The record links to 0 conditions, and to 2 interventions - of which G-Pump™ (glucagon infusion) is the first listed.

NCT02081001 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02081001 about?

NCT02081001 is a clinical study titled "PK/PD Study With G-Pump (Glucagon Infusion) in T1DM Patients". The purpose of the study is to assess the safety, speed of absorption, and onset of action of G-Pump™ (glucagon infusion) at three subcutaneous doses as compared to Novo GlucaGen®, all delivered via an OmniPod® infusion pump to patients with type 1 diabetes.

What is the current status of trial NCT02081001?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2014-03. Estimated completion is 2014-09.

What interventions are being tested in trial NCT02081001?

The interventions under investigation include: G-Pump™ (glucagon infusion) (DRUG), Novo Nordisk GlucaGen® (DRUG).

Who is sponsoring clinical trial NCT02081001?

This trial is sponsored by Xeris Pharmaceuticals, which has 14 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02081001's enrollment target sits among peer trials

19 1894th of 2000 higher than 103 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02081001, the US trial registry maintained by the National Library of Medicine. NCT02081001 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.