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NCT02074696 · ClinicalTrials.gov registry record
BDNF and Motor Learning
A clinical trial, sponsored by University of Minnesota.
- Terminated
- Registry status
- 24
- Enrollment target
NCT02074696: Clinical Trial study, sponsored by University of Minnesota.
NCT02074696 is a clinical trial that was terminated before completion, run by University of Minnesota. The registered enrollment target is 24 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02074696 was terminated before completion, sponsored by University of Minnesota.
- TERMINATED
- Registry status
- 24 participants
- Enrollment target
Study Summary
The purpose of the study is to assess the status of brain-derived neurotrophic factor brain (BDNF) and how the brain behaves in response to skill acquisition. Specifically we will investigate the relationship of the status of BDNF with cortical excitability changes and learning that occur during a motor training paradigm. We aim to 1) determine cortical excitability changes by using transcranial magnetic stimulation (TMS) before and after training; 2) to determine finger tracking accuracy before and after training; and 3) determine the presence of BDNF polymorphism in each participant. We are testing healthy adults in this study, and eventually would like to apply to persons who have neurologic disorders such as stroke or dystonia. By applying a magnetic field to the outside of the head, electrical currents are produced within the brain that can stimulate brain tissue. Using TMS, the brain can be studied to gain a greater understanding of the mechanisms associated with cortical excitability in healthy and patient populations. There is limited knowledge of what influence genetic biomarkers such as BDNF have on cortical excitability changes within the cortex following learning. Studies have indicated that people without this certain gene are less likely to show changes in brain excitability during TMS and during motor learning than people with this gene
Primary Outcome
A computer quantified tracking performance measure in each test. This is a calculation of accuracy by using the equation: AI = 100(P-E)/P. Where E is the root mean square (r.m.s.) error between the target line and the response line, and P is the size of the individual's target pattern, calculated as the r.m.s. difference between the sine wave and the midline separating the upper and lower phases of the sine wave. The magnitude of P is determined by the scale of the vertical axis, which is the su
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2014-04 |
| Est. Completion | 2014-05 |
Why NCT02074696 stopped before completion
NCT02074696 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 24 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02074696 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02074696 about?
NCT02074696 is a clinical study titled "BDNF and Motor Learning". The purpose of the study is to assess the status of brain-derived neurotrophic factor brain (BDNF) and how the brain behaves in response to skill acquisition. Specifically we will investigate the relationship of the status of BDNF with cortical excitability changes and learning that occur during a m...
What is the current status of trial NCT02074696?
This trial is currently terminated. The enrollment target is 24 participants. The study started on 2014-04. Estimated completion is 2014-05.
Who is sponsoring clinical trial NCT02074696?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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