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NCT02065895 · ClinicalTrials.gov registry record · NA

Effect of Gain on Closed-Loop Insulin

A NA study, sponsored by Joslin Diabetes Center.

Completed
Registry status
NA
Development phase
8
Enrollment target

NCT02065895: Completed NA study, sponsored by Joslin Diabetes Center.

NCT02065895 is a NA study that has completed, run by Joslin Diabetes Center. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02065895, a NA study, has completed, sponsored by Joslin Diabetes Center.

COMPLETED
Registry status
NA
Development phase
8 participants
Enrollment target

Study Summary

The purpose of this study is to test the ability of an advanced external Physiologic Insulin Delivery (ePID) algorithm (a step by step process used to develop a solution to a problem) to get acceptable meal responses over a range of gain. Gain is defined as how much insulin is given in response to a change in a patient's glucose level. This study also examines the effectiveness of the external Physiologic Insulin Delivery (ePID) closed-loop insulin delivery computer software. The investigators would like to assess whether fasting target levels can be achieved as the closed-loop gain increases or decreases, and to evaluate the system's ability to produce an acceptable breakfast meal response.

Primary Outcome

Glucose Area Under the Curve (AUC) Breakfast defines the total exposure to glucose during breakfast. Breakfast is typically considered the most difficult meal to control; low AUC is desirable.This outcome measure was analyzed for each of the three calibration error values (high error, no error and low error).

Interventions

  • DEVICE HIGH error
  • DEVICE NO error
  • DEVICE LOW error

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2013-12
Est. Completion 2015-04
Phase NA
Joslin Diabetes Center

73 total trials

What the finished NCT02065895 record still lists

NCT02065895 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 3 interventions - of which HIGH error is the first listed.

NCT02065895 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02065895 about?

NCT02065895 is a clinical study titled "Effect of Gain on Closed-Loop Insulin". The purpose of this study is to test the ability of an advanced external Physiologic Insulin Delivery (ePID) algorithm (a step by step process used to develop a solution to a problem) to get acceptable meal responses over a range of gain. Gain is defined as how much insulin is given in response to a...

What is the current status of trial NCT02065895?

This trial is currently completed. It is a NA study. The enrollment target is 8 participants. The study started on 2013-12. Estimated completion is 2015-04.

What interventions are being tested in trial NCT02065895?

The interventions under investigation include: HIGH error (DEVICE), NO error (DEVICE), LOW error (DEVICE).

Who is sponsoring clinical trial NCT02065895?

This trial is sponsored by Joslin Diabetes Center, which has 73 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02065895's enrollment target sits among peer trials

8 1976th of 2000 higher than 19 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02065895, the US trial registry maintained by the National Library of Medicine. NCT02065895 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.