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NCT02059980 · ClinicalTrials.gov registry record · NA

Developing Effective Response Inhibition Training for Symptom Relief in OCD and Trichotillomania

A NA study, sponsored by University of Wisconsin, Milwaukee.

Completed
Registry status
NA
Development phase
45
Enrollment target

NCT02059980: Completed NA study, sponsored by University of Wisconsin, Milwaukee.

NCT02059980 is a NA study that has completed, run by University of Wisconsin, Milwaukee. The registered enrollment target is 45 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02059980, a NA study, has completed, sponsored by University of Wisconsin, Milwaukee.

COMPLETED
Registry status
NA
Development phase
45 participants
Enrollment target

Study Summary

Obsessive-compulsive disorder (OCD) and its related disorders (e.g., trichotillomania) are characterized by the marked difficulty in inhibiting unwanted or inappropriate responses. There is compelling evidence that poor response inhibition is a core cognitive feature of OCD and its related disorders, but no effective intervention exists that directly attempts to address this problematic cognitive deficiency. This study will examine the feasibility and clinical utility of a computerized cognitive training program designed to improve response inhibition among individuals diagnosed with OCD or trichotillomania.This training program offers systematic practice of response inhibition in the form of a 40-level computer game. Individuals with these conditions will be randomized to either 8 sessions of (a) computerized response inhibition training (RIT) or (b) placebo computer training (PLT). We hypothesize that RIT will outperform PLT in improving response inhibition capabilities and reducing relevant clinical symptoms. In sum, this project is expected to generate important knowledge to guide the development of effective computer-based treatment approaches that may help reduce critical problems of existing treatments such as suboptimal patient retention and treatment under-utilization, thereby improving overall treatment response rates among individuals suffering from OCD and related conditions.

Primary Outcome

This is a clinician-administered rating scale of OCD symptom severity, most widely used in treatment outcome research for OCD, and a clinician-administered rating scale of hair pulling symptoms, widely used in clinical trial research for trichotillomania. Given the inclusion of two different diagnostic conditions, the primary outcome for the current study is the z score of the symptom rating severity obtained from the two rating scales, with higher values indicating greater symptom severity.

Interventions

  • BEHAVIORAL Response inhibition training
  • BEHAVIORAL Placebo Control Training

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2014-08
Est. Completion 2017-08
Phase NA
University of Wisconsin, Milwaukee

21 total trials

What the finished NCT02059980 record still lists

NCT02059980 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which Response inhibition training is the first listed.

NCT02059980 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02059980 about?

NCT02059980 is a clinical study titled "Developing Effective Response Inhibition Training for Symptom Relief in OCD and Trichotillomania". Obsessive-compulsive disorder (OCD) and its related disorders (e.g., trichotillomania) are characterized by the marked difficulty in inhibiting unwanted or inappropriate responses. There is compelling evidence that poor response inhibition is a core cognitive feature of OCD and its related disorders...

What is the current status of trial NCT02059980?

This trial is currently completed. It is a NA study. The enrollment target is 45 participants. The study started on 2014-08. Estimated completion is 2017-08.

What interventions are being tested in trial NCT02059980?

The interventions under investigation include: Response inhibition training (BEHAVIORAL), Placebo Control Training (BEHAVIORAL).

Who is sponsoring clinical trial NCT02059980?

This trial is sponsored by University of Wisconsin, Milwaukee, which has 21 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02059980's enrollment target sits among peer trials

45 1411th of 2000 higher than 578 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02059980, the US trial registry maintained by the National Library of Medicine. NCT02059980 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.