Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02058979 · ClinicalTrials.gov registry record · NA
Pharmacokinetics of Bolus Versus Continuous Cefazolin Infusion in Patients Undergoing Major Surgery
A NA study, sponsored by University of Virginia.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT02058979 is a NA study that has completed, run by University of Virginia. The registered enrollment target is 20 participants.
The verdict
NCT02058979, a NA study, has completed, sponsored by University of Virginia.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
Abstract The administration of an antibiotic preoperatively is an important intervention that helps to reduce the risk of post-operative health-care associated infections (HCAI). These include urinary tract, surgical site and blood stream infection. Based on the current Surgical Infection Prevention Project, (SCIP) recommendations, the choice of the antibiotic is based on the nature and site of the surgery and the presence of a β-lactam allergy (Table 1). Currently, the antibiotic treatment for preventing surgical infections is administered as a single bolus an hour before surgery, and every four hours after the initial dose. This presents a concentration profile that has a high concentration after the bolus, but decays as the kidneys remove the antibiotics. In this present study, investigators would like to compare this traditional method of delivery to a constant infusion model that would sustain a constant level of antibiotics that is defined by the difference between the rate of infusion and rate of clearance.
Interventions
- DRUG BOLUS INFUSION (Ancef)
- DRUG CONTINUOUS INFUSION (Ancef)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2014-11 |
| Est. Completion | 2016-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02058979
The ClinicalTrials.gov registry entry for NCT02058979 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which BOLUS INFUSION (Ancef) is the first listed.
NCT02058979 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02058979 about?
NCT02058979 is a clinical study titled "Pharmacokinetics of Bolus Versus Continuous Cefazolin Infusion in Patients Undergoing Major Surgery". Abstract The administration of an antibiotic preoperatively is an important intervention that helps to reduce the risk of post-operative health-care associated infections (HCAI). These include urinary tract, surgical site and blood stream infection. Based on the current Surgical Infection Prevention...
What is the current status of trial NCT02058979?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2014-11. Estimated completion is 2016-06.
What interventions are being tested in trial NCT02058979?
The interventions under investigation include: BOLUS INFUSION (Ancef) (DRUG), CONTINUOUS INFUSION (Ancef) (DRUG).
Who is sponsoring clinical trial NCT02058979?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.