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NCT02058511 · ClinicalTrials.gov registry record · NA
Infrared Pupillometry During General Anesthesia to Predict Pain
A NA study, sponsored by University of California, San Francisco.
- Terminated
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT02058511: Clinical Trial NA study, sponsored by University of California, San Francisco.
NCT02058511 is a NA study that was terminated before completion, run by University of California, San Francisco. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02058511, a NA study, was terminated before completion, sponsored by University of California, San Francisco.
- TERMINATED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
The study comprises of a series of pupillary measurements using infrared pupillometry in patients undergoing arthroscopic knee surgery of any type. Infrared pupillometry will be used to assess whether a painful stimulus results in pupillary reflex dilation (PRD). The extend of the PRD may be an indicator how painful a stimulus is. This may help to predict the amount of discomfort a patient will be experiencing after emergence from general anesthesia. In addition to measuring the pupillary reflex dilation, we will also measure oscillations of pupil size before and after indiction of anesthesia, as well as during recovery. These spontaneously occuring oscillations in pupil size, also called hippus, appear to be sensitive to anesthetics and opioids. However, the effect of these drugs on hippus has not been systematically addressed. The aim of the study is 1. to identify whether regional anesthesia techniques such as femoral and sciatic nerve blocks will block the PRD. This would allow assessment of block success in the anesthetized patient. 2. to correlate the extent of the pupillary reflex dilation and hippus in the anesthetized patient during and at the end of surgery with early postoperative pain scores and subsequent analgesia requirements. Such correlation would allow to predict the amount of postoperative pain before the patients emerge from general anesthesia.
Primary Outcome
Pain as assessed by visual analogue score at arrival of the patient in the recovery room Scale goes from 0-10, with 10 indicating the worst pain possible
Interventions
- DRUG Anesthesia Premedication, Induction and Maintenance
- PROCEDURE Pupillometry after administration of anesthetic drugs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2012-11 |
| Est. Completion | 2016-11 |
| Phase | NA |
Why NCT02058511 stopped before completion
NCT02058511 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Anesthesia Premedication, Induction and Maintenance is the first listed.
NCT02058511 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02058511 about?
NCT02058511 is a clinical study titled "Infrared Pupillometry During General Anesthesia to Predict Pain". The study comprises of a series of pupillary measurements using infrared pupillometry in patients undergoing arthroscopic knee surgery of any type. Infrared pupillometry will be used to assess whether a painful stimulus results in pupillary reflex dilation (PRD). The extend of the PRD may be an ind...
What is the current status of trial NCT02058511?
This trial is currently terminated. It is a NA study. The enrollment target is 24 participants. The study started on 2012-11. Estimated completion is 2016-11.
What interventions are being tested in trial NCT02058511?
The interventions under investigation include: Anesthesia Premedication, Induction and Maintenance (DRUG), Pupillometry after administration of anesthetic drugs (PROCEDURE).
Who is sponsoring clinical trial NCT02058511?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02058511's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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