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NCT02053532 · ClinicalTrials.gov registry record
Functional Brain Imaging in PTSD
A clinical trial, sponsored by NYU Langone Health.
- Completed
- Registry status
- 50
- Enrollment target
NCT02053532 is a clinical trial that has completed, run by NYU Langone Health. The registered enrollment target is 50 participants.
The verdict
NCT02053532 has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
Study Summary
Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume. In this pilot study we propose to use the combined positron emission tomography/magnetic resonance (PET/MR) scanner and F-18-fluorodeoxyglucose (FDG, an analog of glucose, the most commonly used PET ligand) to examine brain function and directly correlate the data with the intrinsic functional connectivity of brain circuits that are responsible for social, emotional and cognitive processing in both individuals with PTSD and group-matched trauma controls (TC) and healthy controls (HC). Once the machine is validated, we will then use a more specific biomarker to better understand the neurochemical factors that contribute to individual differences in PTSD. Thus, the data obtained from this pilot study will guide our future molecular imaging studies. The link between general brain function, specific molecular target and the intrinsic functional connectivity of brain circuits that are responsible for social, emotional and cognitive processing in PTSD, TC and HC will be explored.
Interventions
- PROCEDURE Positron emission tomography/magnetic resonance imaging
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2013-05 |
| Est. Completion | 2016-02 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02053532
The ClinicalTrials.gov registry entry for NCT02053532 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NYU Langone Health, which has 1,164 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Positron emission tomography/magnetic resonance imaging is the first listed.
NCT02053532 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02053532 about?
NCT02053532 is a clinical study titled "Functional Brain Imaging in PTSD". Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume. In this pilot study we propose to use the combined positron emission tomography/m...
What is the current status of trial NCT02053532?
This trial is currently completed. The enrollment target is 50 participants. The study started on 2013-05. Estimated completion is 2016-02.
What interventions are being tested in trial NCT02053532?
The interventions under investigation include: Positron emission tomography/magnetic resonance imaging (PROCEDURE).
Who is sponsoring clinical trial NCT02053532?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
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