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NCT02053532 · ClinicalTrials.gov registry record
Functional Brain Imaging in PTSD
A clinical trial, sponsored by NYU Langone Health.
- Completed
- Registry status
- 50
- Enrollment target
NCT02053532: Completed study, sponsored by NYU Langone Health.
NCT02053532 is a clinical trial that has completed, run by NYU Langone Health. The registered enrollment target is 50 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02053532 has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
Study Summary
Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume. In this pilot study we propose to use the combined positron emission tomography/magnetic resonance (PET/MR) scanner and F-18-fluorodeoxyglucose (FDG, an analog of glucose, the most commonly used PET ligand) to examine brain function and directly correlate the data with the intrinsic functional connectivity of brain circuits that are responsible for social, emotional and cognitive processing in both individuals with PTSD and group-matched trauma controls (TC) and healthy controls (HC). Once the machine is validated, we will then use a more specific biomarker to better understand the neurochemical factors that contribute to individual differences in PTSD. Thus, the data obtained from this pilot study will guide our future molecular imaging studies. The link between general brain function, specific molecular target and the intrinsic functional connectivity of brain circuits that are responsible for social, emotional and cognitive processing in PTSD, TC and HC will be explored.
Primary Outcome
In this pilot study we propose to use the combined positron emission tomography/magnetic resonance (PET/MR) scanner and F-18-fluorodeoxyglucose (FDG, an analog of glucose, the most commonly used PET ligand) to examine brain function and directly correlate the data with the intrinsic functional connectivity of brain circuits that are responsible for social, emotional and cognitive processing in both individuals with post-traumatic stress disorder (PTSD) and group-matched trauma controls (TC) and
Interventions
- PROCEDURE Positron emission tomography/magnetic resonance imaging
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2013-05 |
| Est. Completion | 2016-02 |
What the finished NCT02053532 record still lists
NCT02053532 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Positron emission tomography/magnetic resonance imaging is the first listed.
NCT02053532 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02053532 about?
NCT02053532 is a clinical study titled "Functional Brain Imaging in PTSD". Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume. In this pilot study we propose to use the combined positron emission tomography/m...
What is the current status of trial NCT02053532?
This trial is currently completed. The enrollment target is 50 participants. The study started on 2013-05. Estimated completion is 2016-02.
What interventions are being tested in trial NCT02053532?
The interventions under investigation include: Positron emission tomography/magnetic resonance imaging (PROCEDURE).
Who is sponsoring clinical trial NCT02053532?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
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