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NCT02053493 · ClinicalTrials.gov registry record · Phase 2
Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction
A Phase 2 study, sponsored by Adrian Hernandez.
- Completed
- Registry status
- Phase 2
- Development phase
- 110
- Enrollment target
NCT02053493: Completed Phase 2 study, sponsored by Adrian Hernandez.
NCT02053493 is a Phase 2 study that has completed, run by Adrian Hernandez. The registered enrollment target is 110 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02053493, a Phase 2 study, has completed, sponsored by Adrian Hernandez.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 110 participants
- Enrollment target
Study Summary
A randomized, double-blinded, placebo-controlled crossover study to assess effect of isosorbide mononitrate with dose up-titration on activity tolerance as assessed by (hip-worn, tri-axial) accelerometry.
Primary Outcome
To evaluate whether isosorbide mononitrate increases daily activity as assessed by 14-day averaged arbitrary accelerometry units in comparison to placebo. An arbitrary accelerometer unit is calculated within the accelerometer device that is worn by the patient and represents level of activity based on patient movement. Higher values indicate more movement. 0 indicates no movement.
Interventions
- DRUG Placebo
- DRUG Isosorbide Mononitrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2014-04 |
| Est. Completion | 2015-03 |
| Phase | Phase 2 |
What the finished NCT02053493 record still lists
NCT02053493 is an interventional study that assigns participants to a tested intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (17% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02053493 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02053493 about?
NCT02053493 is a clinical study titled "Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction". A randomized, double-blinded, placebo-controlled crossover study to assess effect of isosorbide mononitrate with dose up-titration on activity tolerance as assessed by (hip-worn, tri-axial) accelerometry.
What is the current status of trial NCT02053493?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 110 participants. The study started on 2014-04. Estimated completion is 2015-03.
What interventions are being tested in trial NCT02053493?
The interventions under investigation include: Placebo (DRUG), Isosorbide Mononitrate (DRUG).
Who is sponsoring clinical trial NCT02053493?
This trial is sponsored by Adrian Hernandez, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02053493's enrollment target sits among peer trials
110 632nd of 2000 higher than 1,361 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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