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NCT02047981 · ClinicalTrials.gov registry record · Phase 4

Mortality Reduction After Oral Azithromycin: Mortality Study

A Phase 4 study of Childhood Mortality, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 4
Development phase
190,238
Enrollment target
6
Study locations

NCT02047981: Completed Phase 4 study of Childhood Mortality, sponsored by University of California, San Francisco.

NCT02047981 is a Phase 4 study of Childhood Mortality that has completed, run by University of California, San Francisco. The registered enrollment target is 190,238 participants, above the 498-participant average among 9,235 other Phase 4 trials with a reported enrollment target (38100% higher). The trial reports 6 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02047981, a Phase 4 study of Childhood Mortality, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 4
Development phase
190,238 participants
Enrollment target
6
Study locations

Study Summary

Our long-term goal is to more precisely define the role of mass azithromycin treatments as an intervention for reducing childhood mortality. We propose a single multi-site (multi-country), cluster-randomized trial comparing communities randomized to oral azithromycin with those randomized to placebo. We hypothesize that mass azithromycin treatments will reduce childhood mortality.

Primary Outcome

This is a single multi-site trial, with each country as a secondary analysis. Also, an interim analysis of efficacy and futility will be conducted according to a pre-specified plan in the Statistical Analysis Plan.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Azithromycin

Study Locations (6)

Other

  • College of Medicine at the University of Malawi, Blantyre - Blantyre
  • The Carter Center, Niger - Niamey
  • Kongwa Trachoma Project - Kongwa
  • London School of Hygiene & Tropical Medicine - London

California

  • UCSF Proctor Foundation - San Francisco

Maryland

  • Johns Hopkins University - Baltimore

Trial Details

FieldValue
Enrollment Target 190,238 participants
Start Date 2014-12
Est. Completion 2018-09
Phase Phase 4

What the finished NCT02047981 record still lists

NCT02047981 is an interventional study that assigns participants to a tested intervention. Its 190,238 participants enrollment target places it among the larger protocols in the corpus, above the 498-participant average among 9,235 other Phase 4 trials with a reported enrollment target (38100% higher).

The record links to 1 condition, with Childhood Mortality appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02047981 lists 6 locations in 3 states (Other, California, Maryland).

Frequently Asked Questions

What is clinical trial NCT02047981 about?

NCT02047981 is a clinical study titled "Mortality Reduction After Oral Azithromycin: Mortality Study". Our long-term goal is to more precisely define the role of mass azithromycin treatments as an intervention for reducing childhood mortality. We propose a single multi-site (multi-country), cluster-randomized trial comparing communities randomized to oral azithromycin with those randomized to placebo...

What is the current status of trial NCT02047981?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 190,238 participants. The study started on 2014-12. Estimated completion is 2018-09.

What conditions does trial NCT02047981 study?

This clinical trial studies the following conditions: Childhood Mortality.

What interventions are being tested in trial NCT02047981?

The interventions under investigation include: Placebo (DRUG), Azithromycin (DRUG).

Who is sponsoring clinical trial NCT02047981?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02047981 being conducted?

This trial has 6 study locations across California, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT02047981's enrollment target sits among peer trials

190,238 4th of 2000 higher than 1,997 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02047981, the US trial registry maintained by the National Library of Medicine. NCT02047981 (large enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.