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NCT02037373 · ClinicalTrials.gov registry record

Evaluation of the Safety of Octaplas™ Versus Plasma in Patients Undergoing Orthotopic Liver Transplantation

A clinical trial, sponsored by Octapharma.

Terminated
Registry status
43
Enrollment target

NCT02037373: Clinical Trial study, sponsored by Octapharma.

NCT02037373 is a clinical trial that was terminated before completion, run by Octapharma. The registered enrollment target is 43 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02037373 was terminated before completion, sponsored by Octapharma.

TERMINATED
Registry status
43 participants
Enrollment target

Study Summary

Post-Marketing Requirement study to evaluate the safety of octaplas™ versus plasma in patients undergoing orthotopic liver transplantation (OLT). The primary objective is to assess the incidence of hyperfibrinolysis in patients undergoing (OLT) receiving octaplas™ versus regular plasma (e.g., fresh frozen plasma and other FDA and AABB approved plasma products).

Primary Outcome

The incidence of 'clinically relevant hyperfibrinolytic events' in patients receiving octaplas™ will be compared with the incidence rate in patients receiving plasma. For this trial a 'clinically relevant hyperfibrinolytic event' is defined as a decrease of at least 7.5% in the maximum amplitude (MA) as measured by the thromboelastography (TEG) or rotational thromboelastography (ROTEM) within 30 minutes after MA is achieved and the event is associated with bleeding requiring intervention.

Interventions

  • BIOLOGICAL Octaplas™
  • BIOLOGICAL Plasma

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2015-08
Est. Completion 2018-02
Octapharma

43 total trials

Why NCT02037373 stopped before completion

NCT02037373 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 43 participants, a relatively small participant target.

The record links to 0 conditions, and to 2 interventions - of which Octaplas™ is the first listed.

NCT02037373 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02037373 about?

NCT02037373 is a clinical study titled "Evaluation of the Safety of Octaplas™ Versus Plasma in Patients Undergoing Orthotopic Liver Transplantation". Post-Marketing Requirement study to evaluate the safety of octaplas™ versus plasma in patients undergoing orthotopic liver transplantation (OLT). The primary objective is to assess the incidence of hyperfibrinolysis in patients undergoing (OLT) receiving octaplas™ versus regular plasma (e.g., fresh ...

What is the current status of trial NCT02037373?

This trial is currently terminated. The enrollment target is 43 participants. The study started on 2015-08. Estimated completion is 2018-02.

What interventions are being tested in trial NCT02037373?

The interventions under investigation include: Octaplas™ (BIOLOGICAL), Plasma (BIOLOGICAL).

Who is sponsoring clinical trial NCT02037373?

This trial is sponsored by Octapharma, which has 43 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT02037373, the US trial registry maintained by the National Library of Medicine. NCT02037373 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.