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NCT02025439 · ClinicalTrials.gov registry record · NA

Amantadine + rTMS as a Neurotherapeutic for Disordered Consciousness

A NA study, sponsored by Edward Hines Jr. VA Hospital.

Completed
Registry status
NA
Development phase
4
Enrollment target

NCT02025439: Completed NA study, sponsored by Edward Hines Jr. VA Hospital.

NCT02025439 is a NA study that has completed, run by Edward Hines Jr. VA Hospital. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02025439, a NA study, has completed, sponsored by Edward Hines Jr. VA Hospital.

COMPLETED
Registry status
NA
Development phase
4 participants
Enrollment target

Study Summary

The purpose of this study is to examine the safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with Amantadine relative to rTMS Alone and Amantadine Alone for persons in chronic states of seriously impaired consciousness. The hypothesis is that provision of rTMS+Amantadine will provide a safe yet synergistic effect that induces or accelerates functional recovery.

Primary Outcome

If an adverse event occurred, the intensity was also indicated. The intensity of an adverse event was determined using a scale from 1-5 with 5 being the worst. The purpose of the study is to examine safety of rTMS combined with AMA relative to rTMS Alone and AMA alone. Results are not reported "per arm" rather, the arms are combined so as to compare the outcome when the interventions are provided separately (i.e., rTMS alone and amantadine alone) vs interventions are combined (rTMS +Amantadine a

Interventions

  • DEVICE rTMS
  • DRUG Amantadine

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2014-02
Est. Completion 2016-07
Phase NA
Edward Hines Jr. VA Hospital

3 total trials

What the finished NCT02025439 record still lists

NCT02025439 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 2 interventions - of which rTMS is the first listed.

NCT02025439 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02025439 about?

NCT02025439 is a clinical study titled "Amantadine + rTMS as a Neurotherapeutic for Disordered Consciousness". The purpose of this study is to examine the safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with Amantadine relative to rTMS Alone and Amantadine Alone for persons in chronic states of seriously impaired consciousness. The hypothesis is that provision of rTMS+Aman...

What is the current status of trial NCT02025439?

This trial is currently completed. It is a NA study. The enrollment target is 4 participants. The study started on 2014-02. Estimated completion is 2016-07.

What interventions are being tested in trial NCT02025439?

The interventions under investigation include: rTMS (DEVICE), Amantadine (DRUG).

Who is sponsoring clinical trial NCT02025439?

This trial is sponsored by Edward Hines Jr. VA Hospital, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02025439's enrollment target sits among peer trials

4 1996th of 2000 higher than 5 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02025439, the US trial registry maintained by the National Library of Medicine. NCT02025439 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.