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NCT02017730 · ClinicalTrials.gov registry record · Phase 1

To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding in Lung Using PET (Positron Emission Tomography) In Healthy Volunteers

A Phase 1 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target

NCT02017730: Completed Phase 1 study, sponsored by Bristol-Myers Squibb.

NCT02017730 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02017730, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

The purpose of this study is to assess the safety and tolerability of a novel positron emission tomography (PET) tracer \[11C\]BMT-136088 in healthy adult subjects for measurement of availability of Lysophosphatidic Acid (LPA1) receptors in the human lung and to use this tracer to assess LPA1 receptor occupancy using \[11C\]BMT-136088 in the human lung following oral administration of Bristol Myers Squibb (BMS)-986020.

Primary Outcome

The following safety endpoints will be considered, the incidence of adverse events (AEs), serious AEs, AEs leading to discontinuation from the study, and death as well as marked abnormalities in clinical laboratory tests, vital sign measurements, electrocardiograms (ECGs), and physical examinations occurring from screening up to study discharge.

Interventions

  • DRUG BMS-986020
  • DRUG [11C]BMT-136088

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2014-01
Est. Completion 2015-01
Phase Phase 1
Bristol-Myers Squibb

1,025 total trials

What the finished NCT02017730 record still lists

NCT02017730 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 2 interventions - of which BMS-986020 is the first listed.

NCT02017730 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02017730 about?

NCT02017730 is a clinical study titled "To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding in Lung Using PET (Positron Emission Tomography) In Healthy Volunteers". The purpose of this study is to assess the safety and tolerability of a novel positron emission tomography (PET) tracer \[11C\]BMT-136088 in healthy adult subjects for measurement of availability of Lysophosphatidic Acid (LPA1) receptors in the human lung and to use this tracer to assess LPA1 recept...

What is the current status of trial NCT02017730?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2014-01. Estimated completion is 2015-01.

What interventions are being tested in trial NCT02017730?

The interventions under investigation include: BMS-986020 (DRUG), [11C]BMT-136088 (DRUG).

Who is sponsoring clinical trial NCT02017730?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02017730's enrollment target sits among peer trials

20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02017730, the US trial registry maintained by the National Library of Medicine. NCT02017730 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.