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NCT02006680 · ClinicalTrials.gov registry record

Markers of Pubertal Suppression During Therapy for Precocious Puberty

A clinical trial, sponsored by University of Minnesota.

Terminated
Registry status
4
Enrollment target

NCT02006680: Clinical Trial study, sponsored by University of Minnesota.

NCT02006680 is a clinical trial that was terminated before completion, run by University of Minnesota. The registered enrollment target is 4 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02006680 was terminated before completion, sponsored by University of Minnesota.

TERMINATED
Registry status
4 participants
Enrollment target

Study Summary

The best way to measure whether treatment of children with central precocious puberty is working is to do a hormone stimulation test (leuprolide stimulation test) that requires injection of a medication and multiple blood draws to see if the hormonal response is suppressed (blocked). The hypothesis of this study is that random measurement of the free alpha subunit of pituitary glycoprotein, a protein related to the pituitary hormones that stimulate puberty, will provide an adequate alternative to the leuprolide stimulation testfor monitoring efficacy of pubertal suppression with Supprelin LA®.

Primary Outcome

The primary outcome of the study will be the sensitivity and specificity of a subject having elevated random FASPG values (\> 0.6 ng/mL) to identify subjects who are appropriately suppressed based upon a leuprolide-stimulated LH \<4 mIU/mL. This outcome will be based upon results of puberty hormone suppression testing obtained 28-97 days after placement of the Supprelin LA insert.

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2013-12
Est. Completion 2015-12
University of Minnesota

966 total trials

Why NCT02006680 stopped before completion

NCT02006680 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 4 participants, a relatively small participant target.

The record links to 0 conditions, and to 0 interventions.

NCT02006680 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02006680 about?

NCT02006680 is a clinical study titled "Markers of Pubertal Suppression During Therapy for Precocious Puberty". The best way to measure whether treatment of children with central precocious puberty is working is to do a hormone stimulation test (leuprolide stimulation test) that requires injection of a medication and multiple blood draws to see if the hormonal response is suppressed (blocked). The hypothesis ...

What is the current status of trial NCT02006680?

This trial is currently terminated. The enrollment target is 4 participants. The study started on 2013-12. Estimated completion is 2015-12.

Who is sponsoring clinical trial NCT02006680?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT02006680, the US trial registry maintained by the National Library of Medicine. NCT02006680 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.