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COMPLETED Phase 4

Contrast Nephropathy and Nitrates

NCT01999517 · View on ClinicalTrials.gov ↗

Study Summary

Contrast-induced nephropathy (CIN) is a complication of percutaneous coronary angiography that occurs in about 10 to 20% of patients exposed to contrast media. Iodinated contrast is used during coronary angiography to see the coronary arteries. It has been shown that exposure to this agent may cause kidney injury. CIN usually goes away on its own but in some high risk patients it progresses into renal failure. This research study offers a new possible option to prevent CIN. We propose that if intravenous nitroglycerin is given before the procedure it may lower the chances of developing contrast-induced nephropathy.

Interventions

  • DRUG Intravenous Nitroglycerin
  • DRUG IV Fluids

Study Locations (1)

Florida

  • Mount Sinai Medical Center — Miami Beach

Trial Details

FieldValue
Enrollment Target 122 participants
Start Date 2013-06
Est. Completion 2018-06
Phase Phase 4

Sponsor

Mt. Sinai Medical Center, Miami

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT01999517

The ClinicalTrials.gov registry entry for NCT01999517 describes a study currently listed as completed. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 122 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mt. Sinai Medical Center, Miami, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Contrast Induced Nephropathy appearing as the primary indexed condition, and to 2 interventions — of which Intravenous Nitroglycerin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT01999517 reports 1 study location spanning 1 distinct geographic area — top geographies include Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT01999517 about?

NCT01999517 is a clinical study titled "Contrast Nephropathy and Nitrates". Contrast-induced nephropathy (CIN) is a complication of percutaneous coronary angiography that occurs in about 10 to 20% of patients exposed to contrast media. Iodinated contrast is used during coronary angiography to see the coronary arteries. It has been shown that exposure to this agent may cause...

What is the current status of trial NCT01999517?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 122 participants. The study started on 2013-06. Estimated completion is 2018-06.

What conditions does trial NCT01999517 study?

This clinical trial studies the following conditions: Contrast Induced Nephropathy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT01999517?

The interventions under investigation include: Intravenous Nitroglycerin (DRUG), IV Fluids (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT01999517?

This trial is sponsored by Mt. Sinai Medical Center, Miami, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT01999517 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial